【摘要】：正慢性呼吸道感染常常伴有慢性支氣管擴(kuò)張,多達(dá)四分之一的病例由銅綠假單胞菌引起,并可導(dǎo)致病情進(jìn)展更快,病死率升高。Haworth等在支氣管擴(kuò)張伴銅綠假單胞菌感染(非囊胞性纖維化癥)成年患者中,進(jìn)行霧化吸入多黏菌素的療效及耐受性研究。受試者為英國、俄羅斯及烏克蘭等國的35個醫(yī)療中心、12個月內(nèi)≥2次呼吸道標(biāo)本中分離出銅綠假單胞菌的支氣管擴(kuò)張患者且納入研究后21 d內(nèi)出現(xiàn)感染
[Abstract]:Positive and chronic respiratory tract infections are often accompanied by chronic bronchiectasis, with up to 1/4 of cases caused by Pseudomonas aeruginosa and can lead to faster progress. Haworth et al studied the efficacy and tolerance of atomized inhaled polymyxin in adult patients with bronchiectasis complicated with Pseudomonas aeruginosa infection (non-cystocytic fibrosis). The subjects were 35 medical centers in Britain, Russia and Ukraine. Pseudomonas aeruginosa bronchiectasis was isolated from respiratory tract specimens 鈮，

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