【摘要】：目的研究纖維支氣管鏡吸痰治療對重癥肺部感染患者呼吸狀態(tài)與炎性應(yīng)激的影響情況,以了解纖維支氣管鏡吸痰治療在此類患者中的應(yīng)用價值。方法選取2014年6月-2016年3月醫(yī)院治療46例重癥肺部感染患者為研究對象,將46例患者隨機(jī)分為對照組和觀察組,每組各23例,對照組進(jìn)行常規(guī)重癥肺部感染治療,觀察組則在常規(guī)治療的基礎(chǔ)上再進(jìn)行纖維支氣管鏡吸痰治療,將兩組患者治療前和治療后12h、24h及48h的呼吸狀態(tài)與炎性應(yīng)激指標(biāo)進(jìn)行比較。結(jié)果治療后12h、24h及48h觀察組肺功能指標(biāo)FEV1、MMF及FVC水平分別為(2.24±0.18)L、(1.08±0.14)L/s、(2.68±0.21)L、(2.60±0.20)L、(1.24±0.16)L/s、(3.15±0.24)L及(2.84±0.23)L、(1.55±0.19)L/s、(3.36±0.27)L,其均好于對照組,其他呼吸相關(guān)指標(biāo)也均好于對照組,血清炎性應(yīng)激指標(biāo)均低于對照組,差異均有統(tǒng)計學(xué)意義(P0.05)。結(jié)論纖維支氣管鏡吸痰治療可有效地改善重癥肺部感染患者的呼吸狀態(tài)與炎性應(yīng)激程度,因此在重癥肺部感染患者中的應(yīng)用價值較高。
[Abstract]:Objective to study the effect of fiberoptic bronchoscopy sputum aspiration therapy on respiratory state and inflammatory stress in patients with severe pulmonary infection, so as to understand the value of fiberoptic bronchoscopy sputum aspiration therapy in this kind of patients. Methods from June 2014 to March 2016, 46 patients with severe pulmonary infection were randomly divided into control group (n = 23) and observation group (n = 23). The control group was treated with routine severe pulmonary infection. The observation group was treated with fiberoptic bronchoscopy on the basis of routine treatment. The respiratory status of the two groups before treatment and 12 hours after treatment, 24 h and 48 h after treatment were compared with inflammatory stress indexes. Results at 12 hours and 48 hours after treatment, the levels of FEV1,MMF and FVC in the observation group were (2.24 鹵0.18) L, (1.08 鹵0.14) L 鈮，

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