【摘要】：【目的】探討影響穩(wěn)定期慢性阻塞性肺疾病(COPD)患者運(yùn)動(dòng)能力的主要因素�！痉椒ā繖z測(cè)109例穩(wěn)定期COPD患者常規(guī)肺通氣功能、股四頭肌功能和在6 min步行試驗(yàn)(6MWT)前后深吸氣量(IC)的變化,同時(shí)對(duì)所有受試者進(jìn)行改良版英國(guó)醫(yī)學(xué)研究會(huì)(m MRC)呼吸困難評(píng)分、圣喬治呼吸問卷(SGRQ)、匹茲堡睡眠質(zhì)量指數(shù)(PSQI)量表、Epworth嗜睡量表(ESS)及漢密爾頓焦慮量表(HAMA)和抑郁量表(HAMD)評(píng)估�！窘Y(jié)果】多元逐步線性回歸分析結(jié)果表明,年齡(標(biāo)準(zhǔn)化系數(shù)β=-0.264,P=0.007)、HAMD評(píng)分(β=-0.246,P=0.005)、SGRQ活動(dòng)部分評(píng)分(β=-0.194,P=0.029)和股四頭肌力量(β=0.197,P=0.030)對(duì)COPD患者6 min步行距離(6MWD)有顯著預(yù)測(cè)意義�！窘Y(jié)論】年齡、抑郁、日�；顒�(dòng)能力和股四頭肌力量可能是穩(wěn)定期COPD患者運(yùn)動(dòng)能力的主要影響因素。
[Abstract]:[objective] to investigate the main factors affecting the motor ability of patients with (COPD) in stable stage. [methods] to detect the routine pulmonary ventilation function in 109 patients with stable COPD. The function of quadriceps femoris and the changes of inspiratory (IC) before and after 6 min walking test (6MWT) were performed on all subjects with an improved (m MRC) dyspnea score of the British Medical Society, St. George's Respiratory questionnaire (SGRQ), Pittsburgh Sleep quality Index (PSQI), Epworth somnolence scale (ESS), Hamilton anxiety scale (HAMA) and Depression scale (HAMD) were evaluated. Age (standardized coefficient 尾 = -0.264) Pao 0.007), HAMD score (尾 = -0.246 Pao 0.005), SGRQ activity part score (尾 = -0.194 pectoris 0.029) and quadriceps femoris strength (尾 = 0.197), [conclusion] Age, depression, activity of daily activities and quadriceps femoris might be the main factors influencing the motor ability of patients with COPD at stable stage.
【作者單位】： 中山大學(xué)孫逸仙紀(jì)念醫(yī)院呼吸內(nèi)科;中山大學(xué)孫逸仙紀(jì)念醫(yī)院綜合科;
【基金】：廣東省科技計(jì)劃項(xiàng)目(2011B080701062) 廣東省自然科學(xué)基金(S2012010008623)
【分類號(hào)】：R563.9

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