【摘要】：目的探討不同霧化方法吸入布地奈德對(duì)慢性阻塞性肺疾病急性加重期(AECOPD)患者胸肺順應(yīng)性及動(dòng)脈血?dú)庵笜?biāo)的影響。方法 83例慢阻肺急性加重期患者根據(jù)隨機(jī)數(shù)字法分成兩組,其中,40例采用空氣泵驅(qū)動(dòng)霧化治療(空氣泵驅(qū)動(dòng)組),43例采用氧驅(qū)動(dòng)霧化治療(氧驅(qū)動(dòng)組)。對(duì)慢阻肺癥狀評(píng)分(CAT)、血?dú)夥治鲋笜?biāo)及胸肺順應(yīng)性進(jìn)行測(cè)定。結(jié)果治療前后,空氣泵驅(qū)動(dòng)組及氧氣驅(qū)動(dòng)組霧化吸入布地奈德在CAT評(píng)分、胸肺順應(yīng)性(Ct、CI和Cth)、肺通氣指標(biāo)(FEV1.0、PEF、MIP和MEP)及血液酸堿度(pH)和動(dòng)脈血氧分壓(PaO)值2比較差異無統(tǒng)計(jì)學(xué)意義(P0.05),但空氣泵驅(qū)動(dòng)組在改善PaCO_2水平上優(yōu)于氧氣驅(qū)動(dòng)組(P0.05)。結(jié)論孟魯司特鈉聯(lián)合BiPAP呼吸機(jī)治療哮喘-慢性阻塞性肺疾病重疊綜合征有較好的臨床療效,值得推廣和應(yīng)用。
[Abstract]:Objective to investigate the effects of inhaled budesonide on thoracic lung compliance and arterial blood gas in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Eighty-three patients with acute exacerbation of COPD were randomly divided into two groups: 40 cases were treated with air pump driven atomization (air pump driven group) and 43 cases were treated with oxygen driven atomization therapy (oxygen driven group). The indexes of (CAT), blood gas analysis and thoracic lung compliance were measured. Results before and after treatment, budesonide inhalation in air pump driven group and oxygen driven group was used in CAT score, thoracic lung compliance (Ct,CI and Cth), pulmonary ventilation index) (FEV1.0,PEF,). MIP and MEP), (pH) of blood pH and (PaO) value of arterial partial pressure of oxygen had no significant difference (P0.05), but air pump driving group was better than oxygen driven group in improving PaCO_2 level (P0.05). Conclusion Montelukast sodium combined with BiPAP respirator has a good clinical effect in the treatment of asthmatic-chronic obstructive pulmonary disease overlap syndrome, which is worth popularizing and applying.
【作者單位】： 武警河北總隊(duì)醫(yī)院呼吸科;
【分類號(hào)】：R563.9

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本文編號(hào)：2351186