【摘要】：目的探討不同霧化方法吸入布地奈德對慢性阻塞性肺疾病急性加重期(AECOPD)患者胸肺順應性及動脈血氣指標的影響。方法 83例慢阻肺急性加重期患者根據(jù)隨機數(shù)字法分成兩組,其中,40例采用空氣泵驅(qū)動霧化治療(空氣泵驅(qū)動組),43例采用氧驅(qū)動霧化治療(氧驅(qū)動組)。對慢阻肺癥狀評分(CAT)、血氣分析指標及胸肺順應性進行測定。結(jié)果治療前后,空氣泵驅(qū)動組及氧氣驅(qū)動組霧化吸入布地奈德在CAT評分、胸肺順應性(Ct、CI和Cth)、肺通氣指標(FEV1.0、PEF、MIP和MEP)及血液酸堿度(pH)和動脈血氧分壓(PaO)值2比較差異無統(tǒng)計學意義(P0.05),但空氣泵驅(qū)動組在改善PaCO_2水平上優(yōu)于氧氣驅(qū)動組(P0.05)。結(jié)論孟魯司特鈉聯(lián)合BiPAP呼吸機治療哮喘-慢性阻塞性肺疾病重疊綜合征有較好的臨床療效,值得推廣和應用。
[Abstract]:Objective to investigate the effects of inhaled budesonide on thoracic lung compliance and arterial blood gas in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Eighty-three patients with acute exacerbation of COPD were randomly divided into two groups: 40 cases were treated with air pump driven atomization (air pump driven group) and 43 cases were treated with oxygen driven atomization therapy (oxygen driven group). The indexes of (CAT), blood gas analysis and thoracic lung compliance were measured. Results before and after treatment, budesonide inhalation in air pump driven group and oxygen driven group was used in CAT score, thoracic lung compliance (Ct,CI and Cth), pulmonary ventilation index) (FEV1.0,PEF,). MIP and MEP), (pH) of blood pH and (PaO) value of arterial partial pressure of oxygen had no significant difference (P0.05), but air pump driving group was better than oxygen driven group in improving PaCO_2 level (P0.05). Conclusion Montelukast sodium combined with BiPAP respirator has a good clinical effect in the treatment of asthmatic-chronic obstructive pulmonary disease overlap syndrome, which is worth popularizing and applying.
【作者單位】： 武警河北總隊醫(yī)院呼吸科;
【分類號】：R563.9

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相關期刊論文 前10條

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本文編號：2351186