發(fā)布時間：2018-11-13 12:52

【摘要】：目的:本論文旨在分析總結(jié)探討血清炎癥標(biāo)志物C反應(yīng)蛋白(CRP)、降鈣素原(PCT)檢測在老年肺炎診治及預(yù)后評估中的臨床意義及痰液性質(zhì)與炎癥標(biāo)志物之間的關(guān)系,并結(jié)合中醫(yī)中藥理論探討老年肺炎的診治。方法:通過分析患者的入院時一般情況(年齡、性別、是否合并基礎(chǔ)病)、臨床表現(xiàn)、痰液性質(zhì)、痰培養(yǎng)、CURB-65評分、血清C反應(yīng)蛋白(CRP)、血清降鈣素原(PCT)、血白細(xì)胞計數(shù)(WBC)、中醫(yī)分型、預(yù)后(是否死亡),進而中西醫(yī)結(jié)合總結(jié)老年肺炎的臨床特征、中醫(yī)癥型、痰液性質(zhì)與炎性標(biāo)志物關(guān)系及炎性標(biāo)志物在老年肺炎診治及預(yù)后評估中的臨床意義,提高老年肺炎的診治水平。結(jié)果:1血清PCT與患者死亡預(yù)后相關(guān)性最高(r=0.396),且相關(guān)性有統(tǒng)計學(xué)意義(P=0.0000.05),血清CRP與患者死亡預(yù)后相關(guān)性次之(r=0.235),且相關(guān)性有統(tǒng)計學(xué)意義(P0.05),WBC與患者死亡預(yù)后相關(guān)性沒有統(tǒng)計學(xué)意義(P0.05)。進一步研究PCT與患者死亡率關(guān)系中發(fā)現(xiàn),閾值T=4.868ng/m L,也就是說當(dāng)PCT=4.868ng/m L時或許可以預(yù)測患者死亡率。2黃痰組的痰培養(yǎng)細(xì)菌陽性率明顯高于非黃痰組,黃痰組的CRP的平均數(shù)為82.984±62.233mg/L,非黃痰組CRP的平均數(shù)為29.161±35.447mg/L,有統(tǒng)計學(xué)意義(P=0.000
[Abstract]:Objective: to investigate the clinical significance of serum C-reactive protein (CRP), procalcitonin (PCT) in diagnosis, treatment and prognosis evaluation of senile pneumonia and the relationship between sputum properties and inflammatory markers. The diagnosis and treatment of senile pneumonia were discussed in combination with the theory of traditional Chinese medicine. Methods: by analyzing the general condition (age, sex, whether or not associated with basic disease), clinical manifestations, sputum properties, sputum culture, CURB-65 score, serum C-reactive protein (CRP), serum procalcitonin (PCT),. Blood leukocyte count (WBC), type, prognosis (death or not), and then integrated Chinese and Western medicine to summarize the clinical characteristics of pneumonia in the elderly, TCM symptomatic type, The relationship between sputum nature and inflammatory markers and the clinical significance of inflammatory markers in the diagnosis and treatment and prognosis evaluation of senile pneumonia and to improve the level of diagnosis and treatment of senile pneumonia. Results: (1) the correlation between serum PCT and mortality prognosis was the highest (r = 0.396), and the correlation was statistically significant (P < 0.05), and the correlation between serum CRP and mortality prognosis was second (r = 0.235). And the correlation was statistically significant (P0.05), WBC and mortality prognosis was not statistically significant (P0.05). Further study of the relationship between PCT and patient mortality found that threshold T=4.868ng/m L, that is, when PCT=4.868ng/m L may predict the death rate of patients with sputum, the positive rate of sputum culture bacteria in the yellow sputum group was significantly higher than that in the non-yellow sputum group. The average of CRP was 82.984 鹵62.233 mg / L in the yellow phlegm group and 29.161 鹵35.447 mg / L in the non-yellow phlegm group.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R563.1

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相關(guān)期刊論文 前2條

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