感染誘發(fā)的ARDS預(yù)后危險因素分析
發(fā)布時間:2018-10-26 19:08
【摘要】:目的:通過對感染誘發(fā)的ARDS患者的臨床資料分析,探討影響病情發(fā)展及預(yù)后的相關(guān)因素,為預(yù)測和干預(yù)感染誘發(fā)的ARDS患者預(yù)后提供理論依據(jù),以期降低死亡率,提高救治率。 方法:回顧性分析2010年3月到2012年12月寧夏醫(yī)科大學(xué)總醫(yī)院ICU科收治的由感染誘發(fā)的ARDS共52例患者的臨床資料,根據(jù)預(yù)后將其分為存活組(n=27)和死亡組(n=25)。分別統(tǒng)計兩組患者的年齡、性別、合并的慢性基礎(chǔ)疾病、急性器官功能障礙的個數(shù)及種類、APACHEⅡ評分、血氣指標(biāo)、其他生化指標(biāo)、病原學(xué)培養(yǎng)的種類及其耐藥性、廣譜抗生素使用的種類等臨床資料,并分析與患者預(yù)后的關(guān)系。統(tǒng)計學(xué)分析使用SPSS17.0軟件進行分析,計量資料兩組間比較采用獨立樣本的t檢驗,計數(shù)資料采用x2檢驗,多因素分析采用條件Logistic回歸方法。 結(jié)果:①單因素分析顯示合并慢性臟器疾。≒=0.036)、起始病因肺內(nèi)感染(P=0.011)、急性心血管系統(tǒng)功能障礙(P=0.015)、急性胃腸道功能障礙(P=0.038)、血尿素氮(P=0.032)、白蛋白(P=0.028)、并發(fā)白色念珠菌感染(P=0.023)等因素在存活組和死亡組有統(tǒng)計學(xué)差異;②多因素分析顯示:起始病因肺內(nèi)感染(P=0.016,OR:2.203,OR95%CI:1.156-4.201)急性心血管系統(tǒng)功能障礙(P=0.010,OR:1.149,OR95%CI:1.034-1.278)、并發(fā)白色念珠菌感染(P=0.046,OR:0.994,OR95%CI:0.988-1.000)在存活組和死亡組中具有統(tǒng)計學(xué)差異,其余各因素在兩組中均無明顯差異。③52例患者入住ICU期間各類標(biāo)本培養(yǎng)出病原菌110株,前5位分別為鮑曼不動桿菌(19.1%),白色念珠菌(11.9%),銅綠假單胞菌(10.9%),大腸埃希菌(10.0%)肺炎克雷伯菌(8.2%)。 結(jié)論:1、影響感染誘發(fā)ARDS的預(yù)后危險因素有:起始病因為肺內(nèi)感染、合并慢性臟器疾病、急性心血管系統(tǒng)功能障礙、尿素氮水平升高、白蛋白水平的降低、并發(fā)白色念珠菌感染。2、起始病因肺內(nèi)感染、急性心血管系統(tǒng)功能障礙、并發(fā)白色念珠菌感染是影響ARDS預(yù)后的獨立危險因素。
[Abstract]:Objective: to analyze the clinical data of ARDS patients induced by infection, and to explore the related factors influencing the development and prognosis of ARDS, to provide theoretical basis for predicting and intervening the prognosis of ARDS patients induced by infection, in order to reduce the mortality rate and improve the treatment rate. Methods: the clinical data of 52 patients with infectious ARDS admitted in ICU Department of Ningxia Medical University General Hospital from March 2010 to December 2012 were retrospectively analyzed. According to the prognosis, they were divided into survival group (nong27) and death group (nong25). Age, sex, number and type of acute organ dysfunction, APACHE 鈪,
本文編號:2296680
[Abstract]:Objective: to analyze the clinical data of ARDS patients induced by infection, and to explore the related factors influencing the development and prognosis of ARDS, to provide theoretical basis for predicting and intervening the prognosis of ARDS patients induced by infection, in order to reduce the mortality rate and improve the treatment rate. Methods: the clinical data of 52 patients with infectious ARDS admitted in ICU Department of Ningxia Medical University General Hospital from March 2010 to December 2012 were retrospectively analyzed. According to the prognosis, they were divided into survival group (nong27) and death group (nong25). Age, sex, number and type of acute organ dysfunction, APACHE 鈪,
本文編號:2296680
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