血清PCT、D-D及NT-proBNP對社區(qū)獲得性肺部感染患者病情的評估研究
發(fā)布時間:2018-10-05 19:20
【摘要】:目的探討血清PCT、D-D及NT-proBNP對社區(qū)獲得性肺炎(CAP)患者病情的評估價值。方法選取2014年3月-2016年10月醫(yī)院呼吸內科收治的社區(qū)獲得性肺炎患者126例為CAP組;采用PSI評分評估患者病情,PSI得分130分為高危組(Ⅴ級),PSI得分91~130為中危組(Ⅳ級),PSI得分90分為低危組(Ⅰ~Ⅲ級);按住院期間存活情況,分為死亡組和存活組;選取同期于醫(yī)院健康體檢的人群120例為對照組;檢測所有研究對象血清降鈣素原(PCT)、D-二聚體(D-D)和N末端腦鈉肽前體(NT-pro BNP)水平。結果 126例社區(qū)獲得性肺炎患者中高危組33例占26.19%,中危組46例占36.51%,低危組47例占37.30%;CAP組血清PCT、D-D、NT-proBNP水平和PSI得分均顯著高于對照組(P0.05),中危組和高危組高于低危組(P0.05),且高危組高于中危組(P0.05);血清PCT、D-D、NT-proBNP水平與PSI評分均呈正相關性(r=0.767,P=0.015;r=0.658,P=0.021;r=0.532,P=0.038);PCT高危社區(qū)獲得性肺炎的診斷敏感性為92.6%,特異性91.2%;DD敏感性為85.6%,特異性93.5%;NT-proBNP敏感性為96.8%,特異性95.6%;死亡組血清PCT、D-D、NTproBNP水平均顯著高于對照組(P0.05)。結論血清PCT、D-D、NT-proBNP水平與社區(qū)獲得性肺炎的嚴重程度呈正相關性,可作為臨床初始治療和評估預后的參考指標。
[Abstract]:Objective to evaluate the value of serum PCT,D-D and NT-proBNP in the evaluation of (CAP) patients with community-acquired pneumonia. Methods A total of 126 patients with community-acquired pneumonia admitted to Department of Respiratory Medicine from March 2014 to October 2016 were selected as CAP group. According to the PSI score, the patients were divided into two groups: high risk group (grade 鈪,
本文編號:2254571
[Abstract]:Objective to evaluate the value of serum PCT,D-D and NT-proBNP in the evaluation of (CAP) patients with community-acquired pneumonia. Methods A total of 126 patients with community-acquired pneumonia admitted to Department of Respiratory Medicine from March 2014 to October 2016 were selected as CAP group. According to the PSI score, the patients were divided into two groups: high risk group (grade 鈪,
本文編號:2254571
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