【摘要】：目的:探討布地奈德(普米克令舒)聯(lián)合復方異丙托溴銨(可必特)霧化吸入治療超高齡慢性阻塞性肺疾病急性加重(AECOPD)患者的臨床療效。方法:60例患者隨機分為治療組和對照組各30例,治療組給予普米克令舒和可必特加入一次性霧化器中,氧驅(qū)動霧化吸入每日2次,每次20-30min,連續(xù)治療7d。對照組給予α-糜蛋白酶加慶大霉素加生理鹽水10ml氧驅(qū)動霧化吸入治療,每日2次,每次20-30min,連續(xù)治療7d。兩組同時給予抗炎、吸氧和平喘等常規(guī)治療。觀察各組患者總有效率,治療前后臨床癥狀的改善情況、住院時間、血氣分析指標及不良反應。結(jié)果:治療組總有效率、臨床癥狀改善、血氣分析結(jié)果、住院時間與對照組比較有顯著差別(P0.01),不良反應極少。結(jié)論:普米克令舒聯(lián)合可必特霧化吸入治療AECOPD患者有顯著療效,且方便、簡單、安全值得推廣使用。
[Abstract]:Objective: to investigate the clinical effect of budesonide (PMT) combined with compound ipratropium bromide (CPB) atomization inhalation in the treatment of (AECOPD) patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Sixty patients were randomly divided into treatment group (n = 30) and control group (n = 30). In the treatment group, Pulmicort and Corbide were added into a disposable atomizer. Oxygen driven atomization inhalation was administered twice a day for 20-30 min for 7 days. The control group was treated with 偽 -chymotrypsin plus gentamicin plus saline 10ml oxygen-driven atomization inhalation twice daily for 20-30 min for 7 days. Both groups were given routine treatment such as anti-inflammatory, oxygen inhalation and anti-asthmatic therapy at the same time. The total effective rate, the improvement of clinical symptoms, hospital stay, blood gas analysis and adverse reactions were observed. Results: the total effective rate, clinical symptom improvement, blood gas analysis and hospitalization time in the treatment group were significantly different from those in the control group (P0.01). Conclusion: Pulmicort lotion combined with Kapidil atomization inhalation is effective in the treatment of AECOPD patients. It is convenient, simple, safe and worth popularizing.
【作者單位】： 廣州軍區(qū)武漢總醫(yī)院干部病房一科;
【分類號】：R563.9

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