【摘要】：目的探討分析引發(fā)乙醇性肝硬化患者肺部感染的危險因素以及預防與控制感染措施,以降低肺部感染率。方法選取2009年1月-2012年12月收治的110例乙醇性肝硬化患者為研究對象,將其中發(fā)生肺部感染的35例患者為感染組,余75例為未感染組,采用logistic回歸分析法對乙醇性肝硬化患者肺部感染的相關因素進行統(tǒng)計分析。結(jié)果 110例乙醇性肝硬化患者中發(fā)生肺部感染35例,感染率為31.8%;35例感染患者中發(fā)熱、外周血白細胞計數(shù)10×109/L、咳嗽、咳痰的陽性率分別為57.1%、51.4%、48.6%;共培養(yǎng)出病原菌19株,其中革蘭陰性菌占68.4%,革蘭陽性菌占21.1%,真菌占10.5%;肺部感染的發(fā)生與年齡、住院時間、肝衰竭、消化道出血、細菌性腹膜炎、肝性腦病及合并基礎疾病有關(P0.05),與性別無明顯相關性;采用非條件logistic回歸分析法結(jié)果發(fā)現(xiàn),年齡(OR=5.791,95%CI=1.704~19.681)、住院時間(OR=4.335,95%CI=1.341~14.017)、肝衰竭(OR=4.338,95%CI=1.012~19.198)、消化道出血(OR=6.909,95%CI=1.643~29.053)、細菌性腹膜炎(OR=5.593,95%CI=1.189~26.311)、肝性腦病(OR=3.939,95%CI=1.162~13.424)、合并基礎性疾病(OR=5.259,95%CI=1.602~17.072)是乙醇性肝硬化患者住院期間肺部感染的主要危險因素(P0.05)。結(jié)論乙醇性肝硬化患者肺部感染率較高,醫(yī)務人員要充分認識其危險因素,以預防和控制其發(fā)生。
[Abstract]:Objective to analyze the risk factors of pulmonary infection in patients with alcoholic cirrhosis and to prevent and control the infection in order to reduce the pulmonary infection rate. Methods from January 2009 to December 2012, 110 patients with ethanol-induced cirrhosis were selected as study subjects. 35 patients with pulmonary infection were selected as infection group and 75 patients as non-infected group. The correlation factors of pulmonary infection in patients with alcoholic cirrhosis were analyzed by logistic regression analysis. Results there were 35 cases of pulmonary infection in 110 patients with alcoholic cirrhosis, and the infection rate was 31.880%. The white blood cell count of peripheral blood was 10 脳 10 9 / L, the positive rates of cough and expectoration were 57.1% and 51.4% respectively, and 19 strains of pathogenic bacteria were cultured. The incidence of pulmonary infection was related to age, hospital stay, liver failure, gastrointestinal bleeding, bacterial peritonitis, hepatic encephalopathy and basic diseases (P0.05). The results of non-conditional logistic regression analysis showed that, 騫撮緞(OR=5.791,95%CI=1.704~19.681),浣忛櫌鏃墮棿(OR=4.335,95%CI=1.341~14.017),鑲濊“绔，

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