本文選題：肺栓塞 + 利鈉肽��； 參考：《中華臨床醫(yī)師雜志(電子版)》2011年21期

【摘要】：目的明確N-末端腦鈉肽前體(NT-proBNP)聯(lián)合超聲心動(dòng)圖在急性肺栓塞(APE)患者預(yù)后評(píng)估中的價(jià)值。方法收集2005年1月至2011年5月收治的48例急性肺栓塞患者的臨床資料,分別分為死亡組與存活組,高NT-proBNP組與低NT-proBNP組,高肺動(dòng)脈收縮壓(PASP)組與低PASP組;分別比較兩組間一般指標(biāo)、腎功能、NT-proBNP值、PASP值、大面積APE發(fā)生率以及死亡率的差異。結(jié)果各組間性別、年齡以及腎功能指標(biāo)均無統(tǒng)計(jì)學(xué)差異(P0.05);死亡組大面積APE發(fā)生率、PASP及NT-proBNP均明顯高于存活組,且差異有統(tǒng)計(jì)學(xué)意義(P0.05);高NT-proBNP組大面積APE發(fā)生率及死亡率均明顯高于低NT-proBNP組(P0.05);高PASP組大面積APE發(fā)生率及死亡率均明顯高于低PASP組(P0.05);相關(guān)分析顯示PASP與NT-proBNP兩者呈顯著正相關(guān)(r=0.423,P0.01)。結(jié)論 NT-proBNP聯(lián)合超聲心動(dòng)圖對(duì)APE患者預(yù)后的評(píng)估有較大價(jià)值。
[Abstract]:Objective to evaluate the prognostic value of NT-terminal brain natriuretic peptide precursor (NT-proBNP) combined with echocardiography in patients with acute pulmonary embolism (ape). Methods from January 2005 to May 2011, 48 patients with acute pulmonary embolism were divided into death group and survival group, high NT-proBNP group and low NT-proBNP group, high pulmonary artery systolic pressure (PASP) group and low PASP group. The difference of NT-proBNP and PASP, the incidence of large area ape and mortality. Results there was no significant difference in sex, age and renal function among the three groups (P0.05), and the incidence of large area ape in the death group was significantly higher than that in the survival group, PASP and NT-proBNP were significantly higher than those in the survival group. The incidence and mortality of large area ape in high NT-proBNP group was significantly higher than that in low NT-proBNP group (P0.05), and the incidence and mortality of large area ape in high PASP group was significantly higher than that in low PASP group (P0.05), and the correlation analysis showed that there was a significant positive correlation between PASP and NT-proBNP (r0.423 / P0.01). Conclusion NT-proBNP combined with echocardiography is of great value in evaluating the prognosis of ape patients.
【作者單位】： 中山大學(xué)孫逸仙紀(jì)念醫(yī)院急診科;廣州市越秀區(qū)紅十字會(huì)醫(yī)院內(nèi)科;
【分類號(hào)】：R563.5

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 劉東紅,陸X,林紅,吳妙齡,龐家傳,闞緒光;多普勒超聲心動(dòng)圖在診斷原發(fā)性肺動(dòng)脈高壓的應(yīng)用[J];中國(guó)醫(yī)學(xué)影像技術(shù);2004年04期

【共引文獻(xiàn)】

相關(guān)期刊論文 前10條

1 易明福;魏曉梅;;肺栓塞28例診治體會(huì)[J];中國(guó)醫(yī)師雜志;2006年05期

2 韓淑英,鄭敏文,文史峰;EBCT在5例肺動(dòng)脈栓塞診斷中的應(yīng)用[J];第四軍醫(yī)大學(xué)學(xué)報(bào);2004年06期

3 王少波;;復(fù)方丹參注射液佐治急性肺栓塞療效[J];第四軍醫(yī)大學(xué)學(xué)報(bào);2005年S1期

4 葛t，

本文編號(hào)：2111150