本文選題：支氣管哮喘 + 呼吸峰流速（PEF）�。� 參考：《大連醫(yī)科大學(xué)》2012年碩士論文

【摘要】：研究目的：探討哮喘控制測(cè)試(asthma control test, ACT)與最大呼氣峰流速(PEF)作用的相關(guān)性，幫助支氣管哮喘患者更佳準(zhǔn)確、簡(jiǎn)便的進(jìn)行自我監(jiān)測(cè)，，提高患者的依從性。 研究方法： 1.研究設(shè)計(jì)：本研究設(shè)計(jì)為非雙盲、前瞻性、開放、研究。 2.研究對(duì)象：選擇我院自2011年8月到2012年4月之間門診收入的確診為支氣管哮喘的患者20例，患者均服用吸入性激素進(jìn)行緩解期的降階梯治療。按照患者門診時(shí)肺功能FEV1%結(jié)果把疾病分為輕度、中度和重度哮喘，比較各組ACT差別。 3.監(jiān)測(cè)、記錄設(shè)備：上海丸博科技有限公司科卡峰速儀(60-850L/min),型號(hào)PEF-3；國(guó)際哮喘聯(lián)盟提供哮喘監(jiān)測(cè)日記。 4.研究步驟：對(duì)入組患者均進(jìn)行PEF監(jiān)測(cè)，測(cè)定時(shí)間是每天2次,為早晨6:30-7:30和晚上18:30-19:30，每次測(cè)定3次，取最大值記錄于哮喘日記，并如實(shí)填寫哮喘控制測(cè)試。每四周隨訪1次，了解其PEF及ACT監(jiān)測(cè)情況,。PEFpred%個(gè)人預(yù)計(jì)值80%為哮喘控制,個(gè)人預(yù)計(jì)個(gè)值80%為哮喘未控制，哮喘控制測(cè)試20分為哮喘未控制;20~25分為哮喘控制。 結(jié)果：ACT評(píng)分20分組與ACT評(píng)分20~25分組PEFpred%比較,差異有統(tǒng)計(jì)學(xué)意義(P0.01)。PEFpred%個(gè)人預(yù)計(jì)值80%組與PEFpred%個(gè)人預(yù)計(jì)值80%組ACT評(píng)分比較,差異有統(tǒng)計(jì)學(xué)意義(P0.01)。ACT評(píng)分與PEFpred%具有線性相關(guān)關(guān)系, P 0.001。PEF評(píng)分在輕、中度之間無(wú)顯著差異（P0.05），PEF評(píng)分在中、重度之間無(wú)顯著差異（P0.01）, PEF評(píng)分在輕度與重度之間為P＝0.006，存在顯著性差異。 結(jié)論: ACT積分與支氣管哮喘患者的PEF值有較好的相關(guān)性，同時(shí)PEF監(jiān)測(cè)對(duì)于輕、中度的哮喘患者更具有監(jiān)測(cè)意義。
[Abstract]:Objective: to investigate the relationship between asthma control test (asthma control test, ACT) and peak expiratory flow rate (PEF) in order to improve the compliance of asthma patients. Methods: 1. Research design: this research design is non-double blind, prospective, open, research. 2. Participants: twenty patients with bronchial asthma diagnosed from August 2011 to April 2012 were all treated with inhaled sex hormones. The disease was divided into mild, moderate and severe asthma according to the FEV 1% results of outpatient, and the difference of ACT in each group was 3. 3%. Monitoring, recording equipment: Shanghai Maru Technology Co., Ltd. Koka peak speed meter (60-850 L / min), model PEF-3; International Asthma Alliance provides asthma monitoring diary. 4. Steps of the study: PEF was monitored twice a day for 6: 30-7: 30 in the morning and 18: 30-19: 30 in the evening. The maximum value was recorded in the asthma diary and the asthma control test was filled out truthfully. The patients were followed up once every four weeks to find out the PEF and ACT monitoring. The predicted values of PEF and ACT were 80% of asthma control, 80% of individual predictive values were uncontrolled asthma, and 20 of asthma control tests were divided into uncontrolled asthma and uncontrolled asthma. Results compared with ACT score 20 and ACT 20 / 25, the difference was statistically significant (P0.01) .PEFpred% personal predictive value was 80% and PEFpred% was 80%. The difference was statistically significant (P0.01) .ACT score had a linear correlation with PEFpred%, P 0.001. There was no significant difference between mild and moderate PEF scores (P0.05), there was no significant difference between severe and moderate PEF scores (P0.01), PEF scores between mild and severe PEF scores were 0.006, there was significant difference. Conclusion: ACT score has a good correlation with PEF in asthma patients, and PEF monitoring is more significant for mild and moderate asthma patients.
【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R562.25

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