動脈血二氧化碳分壓分級對老年慢性阻塞性肺病患者記憶障礙的影響
發(fā)布時間:2018-06-12 04:05
本文選題:動脈血二氧化碳分壓(Pa + CO); 參考:《中國老年學(xué)雜志》2014年23期
【摘要】:正慢性阻塞性肺病(COPD)可導(dǎo)致低氧血癥和(或)高碳酸血癥〔1〕,進(jìn)而引起呼吸、循環(huán)、肝腎及中樞神經(jīng)系統(tǒng)等受損,嚴(yán)重者可引起肺性腦病,表現(xiàn)為頭疼,記憶力減退。長期缺氧可以引起氧自由基產(chǎn)生、神經(jīng)元損害、炎性反應(yīng)及神經(jīng)膠質(zhì)細(xì)胞活化等腦部結(jié)構(gòu)和功能發(fā)生改變,導(dǎo)致認(rèn)知功能障礙〔2〕。記憶功能是認(rèn)知功能的最敏感指標(biāo),本研究分析缺氧狀況對老年COPD患者記憶功能的影響狀況。1對象與方法
[Abstract]:Chronic obstructive pulmonary disease (COPD) can cause hypoxemia and (or) hypercapnia [1], which may cause respiratory, circulation, liver and kidney and central nervous system damage, and severe patients can cause pulmonary encephalopathy, manifested as headache, memory impairment. Long-term hypoxia can cause oxygen free radical production, neuron damage, inflammatory reaction and glial fine. Structural and functional changes in the brain, such as cell activation, lead to cognitive dysfunction [2]. Memory function is the most sensitive index of cognitive function. This study analyzes the effect of hypoxia on memory function in elderly COPD patients.1 objects and methods
【作者單位】: 唐山市豐南區(qū)醫(yī)院;河北聯(lián)合大學(xué)護(hù)理與康復(fù)學(xué)院;
【基金】:河北省衛(wèi)生廳重點(diǎn)課題(20100463)
【分類號】:R563.9
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本文編號:2008253
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