本文選題：慢性阻塞性肺疾病 + 下呼吸道感染　； 參考：《中華醫(yī)院感染學(xué)雜志》2016年17期

【摘要】：目的研究分析血清降鈣素原(PCT)、超敏C-反應(yīng)蛋白(Hs2CRP)和血清淀粉樣蛋白A(SAA)水平在老年慢性阻塞性肺疾病急性加重期下呼吸道感染診斷中變化的臨床意義。方法隨機(jī)選取2013年10月-2015年10月臨床治療治的95例老年慢性阻塞性肺疾病患者為研究對(duì)象,呼吸道細(xì)菌感染患者48例設(shè)為觀察組,余47例為對(duì)照組;對(duì)兩組患者的血清PCT、Hs2CRP和SAA水平進(jìn)行檢測(cè),分析兩組患者指標(biāo)變化的臨床意義。結(jié)果觀察組患者血清PCT(3.35±0.03)ng/ml、Hs2CRP(64.75±19.03)mg/L和SAA(85.47±13.52)mg/L水平顯著高于對(duì)照組(P0.05),觀察組患者治療后的血清PCT、Hs2CRP和SAA水平分別為(0.28±0.04)ng/ml、(14.35±3.06)mg/L、(12.86±2.95)mg/L,較治療前均顯著改善(P0.05);同時(shí)PCT、Hs2CRP及SAA水平檢測(cè)也表現(xiàn)出較高的特異性和靈敏性。結(jié)論老年慢性阻塞性肺疾病急性加重期下呼吸道感染采用血清PCT、Hs2CRP及SAA水平檢測(cè)對(duì)臨床診斷和治療具有積極的意義。
[Abstract]:Objective to study the clinical significance of serum calcitonin proto-PCTX, hypersensitive C-reactive protein (Hs2CRP) and serum amyloid protein (Alosa) in the diagnosis of lower respiratory tract infection (LRTI) in elderly patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Ninety-five elderly patients with chronic obstructive pulmonary disease were randomly selected from October 2013 to October 2015. 48 patients with respiratory tract bacterial infection were selected as observation group and 47 patients as control group. The serum levels of PCTs2 CRP and SAA were measured in two groups, and the clinical significance of the changes in the two groups was analyzed. Results the levels of serum PCTHs2CRPN in the observation group (3.35 鹵0.03ng / ml) were significantly higher than those in the control group (64.75 鹵19.03 mg / L and 85.47 鹵13.52 mg / L, respectively). The serum levels of PCTHs2CRP and SAA in the observation group were 0.28 鹵0.04 ng / ml, 14.35 鹵3.06 mg / L, 12.86 鹵2.95 mg / L, respectively, which were significantly improved compared with those before treatment, and the detection of PCTHs2CRP and SAA also showed high specificity and sensitivity. Conclusion the detection of serum PCTV-Hs2CRP and SAA levels in elderly patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) is of positive significance for clinical diagnosis and treatment.
【作者單位】： 山東省蘭陵縣人民醫(yī)院呼吸科;
【基金】：山東省衛(wèi)生廳基金資助項(xiàng)目(SW-2010-028)
【分類號(hào)】：R563.9
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本文編號(hào)：1994425