本文選題：急診重癥監(jiān)護(hù)病房 + 侵襲性真菌感染��； 參考：《新疆醫(yī)科大學(xué)》2012年碩士論文

【摘要】：目的：對我院急診科重癥監(jiān)護(hù)病房患者肺部侵襲性真菌感染的高危因素進(jìn)行分析，以明確哪些致真菌感染的危險因素為急診重癥監(jiān)護(hù)病房患者肺部侵襲性真菌感染的獨立危險因素，以采取積極有效的預(yù)防控制措施。方法：采用回顧性調(diào)查研究的方法，對我院急診科重癥監(jiān)護(hù)病房2010年1月至2011年12月收住35例確診為肺部侵襲性真菌感染的患者的臨床病歷資料進(jìn)行分析，，并抽取同期在我院急診科重癥監(jiān)護(hù)病房住院的35例發(fā)生肺部細(xì)菌感染但未合并真菌感染患者的臨床病歷資料，對兩組患者的病歷資料進(jìn)行對比，并對可能導(dǎo)致患者肺部侵襲性真菌感染的15項指標(biāo)進(jìn)行單因素及l(fā)ogistic多重回歸分析，最后篩選出侵襲性真菌感染的獨立危險因素。結(jié)果：對15項侵襲性真菌感染潛在的危險因素進(jìn)行單因素分析后，得出合并糖尿病、深靜脈置管、廣譜抗生素的應(yīng)用時間＞2周、廣譜抗生素應(yīng)用種類＞2種、糖皮質(zhì)激素的應(yīng)用是肺部侵襲性真菌感染的危險因素，再進(jìn)行Logistic多因素回歸分析后，最后只有合并糖尿病、深靜脈置管、廣譜抗生素的應(yīng)用時間＞2周及廣譜抗生素應(yīng)用種類＞2種是肺部侵襲性真菌感染的獨立危險因素。結(jié)論：在急診科重癥監(jiān)護(hù)病房，對存在侵襲性真菌感染高危因素的患者應(yīng)加強(qiáng)病原菌監(jiān)測，并適當(dāng)采取預(yù)防措施，達(dá)到控制真菌感染的目的。
[Abstract]:Objective: to analyze the risk factors of invasive fungal infection in the patients in the intensive care unit of the emergency department of our hospital, so as to identify the risk factors for fungal infection in the emergency intensive care unit (ICU) as an independent risk factor for the invasive fungal infection of the lung in the emergency intensive care unit, and to adopt a positive and effective preventive and control measure. The clinical data of 35 cases of pulmonary invasive fungal infection in the intensive care unit of the emergency department of our hospital from January 2010 to December 2011 were analyzed by sex investigation and study, and 35 cases of pulmonary bacterial infection in the emergency department of our hospital during the same period were taken from the patients with pulmonary infection but not with fungal infection. Clinical records were compared for two groups of patients, and single factor and logistic multiple regression analysis were performed on 15 indicators that might lead to invasive fungal infection in the patients. Finally, independent risk factors for invasive fungal infection were screened. Results: the potential risk factors for 15 invasive fungal infections were given. After the analysis of the factors, we found that the combination of diabetes, deep venous catheterization, broad spectrum antibiotic application time > 2 weeks, broad spectrum antibiotic application species > 2 species, the application of glucocorticoid is the risk factor of pulmonary invasive fungal infection, and then after Logistic multiple regression analysis, the last only combined diabetes, deep venous catheterization, broad-spectrum antibiotics. The application time > 2 weeks and the wide spectrum antibiotic application species > 2 are independent risk factors for the pulmonary invasive fungal infection. Conclusion: in the emergency intensive care unit, the patients with high risk factors for invasive fungal infection should be monitored and the prevention measures should be taken to achieve the purpose of controlling the fungal infection.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R519

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