有創(chuàng)無(wú)創(chuàng)序貫機(jī)械通氣搶救重癥老年呼吸衰竭患者的有效性與安全性
發(fā)布時(shí)間:2018-05-31 00:04
本文選題:呼吸衰竭 + 有創(chuàng)機(jī)械通氣。 參考:《中國(guó)老年學(xué)雜志》2014年17期
【摘要】:目的研究有創(chuàng)無(wú)創(chuàng)序貫機(jī)械通氣搶救重癥呼吸衰竭老年患者的有效性與安全性。方法選擇2011年1月至2014年1月在該院接受機(jī)械通氣治療的重癥呼吸衰竭老年患者90例作為研究對(duì)象,根據(jù)機(jī)械通氣的方法不同將納入者分為接受有創(chuàng)無(wú)創(chuàng)序貫機(jī)械通氣的觀察組和持續(xù)有創(chuàng)機(jī)械通氣的對(duì)照組,比較兩組患者的治療情況、呼吸及血?dú)庀嚓P(guān)指標(biāo)、應(yīng)激反應(yīng)程度。結(jié)果 (1)治療情況:觀察組撤管成功率明顯高于對(duì)照組;呼吸機(jī)相關(guān)肺炎發(fā)生率、再插管率、死亡率、PaO2/FiO2恢復(fù)正常時(shí)間、胸片征象消失時(shí)間、機(jī)械通氣時(shí)間、住院時(shí)間均明顯低于對(duì)照組;(2)呼吸及血?dú)庀嚓P(guān)指標(biāo):觀察組患者的pH值、PaO2、SaO2明顯高于對(duì)照組,PaCO2、RR、HR值明顯低于對(duì)照組;(3)應(yīng)激反應(yīng):觀察組患者腎上腺素、去甲腎上腺素、腎素以及血管緊張素Ⅱ水平均低于對(duì)照組。結(jié)論有創(chuàng)無(wú)創(chuàng)序貫機(jī)械通氣有助于臨床癥狀和體征的恢復(fù)、縮短機(jī)械通氣時(shí)間、減少并發(fā)癥發(fā)生、改善肺泡氧合情況、緩解應(yīng)激反應(yīng),是呼吸衰竭安全、有效的治療措施。
[Abstract]:Objective to study the efficacy and safety of noninvasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure. Methods 90 elderly patients with severe respiratory failure who received mechanical ventilation from January 2011 to January 2014 were selected as the study subjects. According to the different methods of mechanical ventilation, the participants were divided into two groups: the observation group receiving invasive and non-invasive sequential mechanical ventilation and the control group with continuous invasive mechanical ventilation. The treatment, respiratory and blood gas related indexes and stress response were compared between the two groups. Results 1) treatment: the success rate of withdrawing tube in the observation group was significantly higher than that in the control group, the incidence of ventilator-associated pneumonia, the rate of re-intubation, the death rate and the time of Pao _ 2 / FiO _ 2 returning to normal, the time of disappearance of chest radiographs, the time of mechanical ventilation, The relative indexes of respiratory and blood gas: the pH value of the patients in the observation group was significantly higher than that in the control group (P < 0.05). The RRHR of the patients in the observation group was significantly lower than that in the control group (P < 0.05). The levels of renin and angiotensin 鈪,
本文編號(hào):1957406
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