本文選題：冷哮證 + 熱哮證�。� 參考：《山東中醫(yī)藥大學(xué)》2013年碩士論文

【摘要】：目的：本課題通過檢測哮喘發(fā)作期小兒過敏原IgE及食物不耐受IgG，探討其與中醫(yī)分型冷哮證、熱哮證的關(guān)系。 方法：選取山東中醫(yī)藥大學(xué)第二附屬醫(yī)院2012年3月至2013年3月間的住院哮喘患兒進(jìn)行研究�；純阂罁�(jù)證型分為冷哮組30例，熱哮組34例，都在治療前檢查特異性IgE、IgG。觀察不同證型間過敏原和食物不耐受各種指標(biāo)的陽性率及過敏原陽性種類均值。采用SPSS17.0統(tǒng)計軟件，應(yīng)用t檢驗和χ2檢驗，P0.05為兩組間差異有顯著性差異。 結(jié)果：本次研究共收集符合納入標(biāo)準(zhǔn)病例64例，最大年齡10歲，最小年齡1.3歲。其中冷哮組患兒30例，男18，女12例，平均年齡4.916±2.63歲；熱哮組患兒34例，男21例，，女13例，平均年齡4.709±2.31歲。兩組患兒在男女年齡、性別差異P值均＞0.05，無顯著性差異。所有64例患兒都檢測兩組敏原。有53例患兒（82.5%）檢測出吸入性過敏原陽性，其中冷哮證組檢出29例占96.7%，熱哮證組檢出24例占70.5%，兩組對比有顯著性差異；多種吸入性過敏原研究中，冷哮證組檢出20例占66.7%，熱哮證組檢出12例占35.3%，對比有統(tǒng)計學(xué)差異（P＜0.05）；冷哮證組平均吸入性過敏原數(shù)2.47±1.358個，熱哮證組平均1.500±1.503個，有顯著性差異（P＜0.05）；食入組過敏原在兩組證型間無顯著性差異；食物不耐受各項比較兩組間無顯著性差異。 結(jié)論：1.冷哮組患兒中吸入組IgE抗體陽性率高于熱哮組，兩組比較有顯著性差異，食入組IgE抗體陽性率在不同證型間比較無顯著性差異。2.冷哮組患兒吸入組多種過敏原（≥2種）檢出率高于熱哮組，兩組比較有顯著性差異；食入組多種過敏原（≥2種）檢出率冷哮組與熱哮組比較無顯著性差異。3.冷哮組患兒吸入組過敏原平均檢出種類多于熱哮組，兩組比較有顯著性差異。4.兩組患兒共檢出不耐受食物14種。各種食物不耐受陽性率在不同證型間比較無顯著性差異。5.兩組患兒食物不耐受IgG抗體檢出陽性例數(shù)比較無顯著性差異，多種（≥2種）食物不耐受檢出陽性例數(shù)不同證型間比較無顯著性差異。
[Abstract]:Objective: to investigate the relationship between IgE and food intolerance in children with asthma. Methods: children with asthma were selected from the second affiliated Hospital of Shandong University of traditional Chinese Medicine from March 2012 to March 2013. According to the syndrome type, the children were divided into cold asthma group (30 cases) and heat asthma group (34 cases). To observe the positive rate of allergen and food intolerance and the average value of allergen positive among different syndromes. Using SPSS17.0 statistical software, using t test and 蠂 2 test (P0.05), there was significant difference between the two groups. Results: a total of 64 cases were collected, the maximum age was 10 years old and the minimum age was 1.3 years old. There were 30 cases of cold asthma group (male 18, female 12, mean age 4.916 鹵2.63), and 34 cases of heat asthma group (male 21, female 13, mean age 4.709 鹵2.31). There was no significant difference between the two groups (P > 0.05). Two groups of allergens were detected in all 64 children. Among them, 29 cases were found to be positive in cold asthma group and 24 cases were 70.5 in heat wheezing syndrome group, there were significant differences between the two groups, among which, there were significant differences between the two groups in the study of multiple inhaled allergens, the results showed that the two groups were positive for inhaled allergens, and 96.7% were found in cold wheezing syndrome group and 24 cases in heat asthma syndrome group, and there were significant differences between the two groups. 20 cases were detected in cold asthma group and 12 cases in heat asthma group (P < 0.05), the average number of inhaled allergens was 2.47 鹵1.358 in cold asthma group and 1.500 鹵1.503 in heat asthma group. There was significant difference (P < 0.05), there was no significant difference between the two groups in the allergen of the ingestion group, and there was no significant difference in the items of food intolerance between the two groups. Conclusion 1. In cold asthma group, the positive rate of IgE antibody in inhalation group was higher than that in hot asthma group, there was significant difference between the two groups, and there was no significant difference in positive rate of IgE antibody between different syndromes. 2. The detection rate of multiple allergens (鈮

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