本文選題：肺結(jié)核 + 耐藥��； 參考：《江蘇醫(yī)藥》2014年23期

【摘要】：目的觀察耐藥肺結(jié)核病的臨床治療效果,探討優(yōu)化藥物治療方案。方法選擇65例復(fù)治菌陽具有耐藥性的病例,給予對氨基水楊酸異煙肼、利福噴丁、左氧氟沙星、乙胺丁醇、丙硫異煙胺、卷曲霉素方案治療12個月后,觀察痰菌總陰轉(zhuǎn)率、病灶總吸收率、空洞閉合率,隨訪1年。結(jié)果痰菌總陰轉(zhuǎn)率為62.30%,病灶總吸收率為80.33%,空洞均有明顯的縮小或閉合,未出現(xiàn)新的空洞,空洞閉合率為39.34%。隨訪1年無一例復(fù)陽,病變尚有一定的吸收。結(jié)論治療方案的痰菌總陰轉(zhuǎn)率、病灶總吸收率、空洞閉合率均較高,有利于耐藥肺結(jié)核病的治療。
[Abstract]:Objective to observe the clinical effect of drug-resistant pulmonary tuberculosis and to explore the optimization of drug therapy. Methods Sixty-five patients with drug resistance were treated with isoniazid aminosalicylate, rifapentine, levofloxacin, ethambutanol, propylthiocarbamate and entramycin for 12 months, and the total negative rate of sputum was observed. The total absorption rate and cavity closure rate were followed up for 1 year. Results the total negative conversion rate of sputum was 62.30%, the total absorption rate of the lesion was 80.33, the cavity was obviously reduced or closed, no new cavity appeared, and the cavity closure rate was 39.34%. All cases were followed up for 1 year, and there was still some absorption of the lesion. Conclusion the total negative rate of sputum bacteria, the total absorption rate and the cavity closure rate of the treatment regimen are all higher, which is beneficial to the treatment of drug-resistant pulmonary tuberculosis.
【作者單位】： 南京市胸科醫(yī)院藥學(xué)部;南京市胸科醫(yī)院結(jié)核科;
【分類號】：R521

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相關(guān)期刊論文 前1條

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本文編號：1914681