本文選題：肺疾病 + 慢性阻塞性　； 參考：《重慶醫(yī)學(xué)》2017年21期

【摘要】：目的探討慢性腎臟病(CKD)對(duì)慢性阻塞性肺疾病(COPD)急性加重(AECOPD)及住院的影響。方法選取2011年1月至2013年6月該院經(jīng)臨床確診的COPD合并CKD患者50例(觀察組),及未合并CKD的COPD患者50例(對(duì)照組)�；仡櫺苑治龌颊�1年內(nèi)的肺功能、運(yùn)動(dòng)耐力及住院情況等資料,并進(jìn)行比較。結(jié)果觀察組病死率、AECOPD總發(fā)生率及重度AECOPD發(fā)生率、住院率、住院時(shí)間、自我評(píng)估測(cè)試(CAT)評(píng)分、改良英國醫(yī)學(xué)研究理事會(huì)(mMRC)呼吸困難指數(shù)、C反應(yīng)蛋白(CRP)及血肌酐水平均高于對(duì)照組,差異均有統(tǒng)計(jì)學(xué)意義(P0.05);觀察組第1秒用力呼氣容積(FEV1)占預(yù)計(jì)值百分比(FEV1%pred)、6min步行試驗(yàn)(6MWD)及肌酐清除率均低于對(duì)照組,差異均有統(tǒng)計(jì)學(xué)意義(P0.05);兩組FEV1/用力肺活量(FVC)比值比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論確診后1年COPD合并CKD患者的病情較未合并CKD患者明顯加重,預(yù)后較差。
[Abstract]:Objective to investigate the effect of chronic kidney disease (CKD) on acute exacerbation and hospitalization of chronic obstructive pulmonary disease (COPD). Methods from January 2011 to June 2013, 50 patients with COPD combined with CKD were selected from January 2011 to June 2013 (observation group) and COPD group (50 cases without CKD) (control group). The data of lung function, exercise endurance and hospitalization were retrospectively analyzed and compared. Results the mortality rate, total incidence of AECOPD, duration of hospitalization, self-assessment test score, dyspnea index of modified British Medical Research Council (MRC) and serum creatinine levels in the observation group were higher than those in the control group. The percentage of forced expiratory volume (FEV1) and creatinine clearance were significantly lower in the observation group than in the control group (P 0.05), and the ratio of forced expiratory volume and FEV1 in the observation group was significantly lower than that in the control group (P 0.05), and the ratio of forced vital capacity of the two groups was higher than that of the control group. The difference was not statistically significant (P 0.05). Conclusion one year after diagnosis, the patients with COPD combined with CKD are worse than those without CKD, and the prognosis is worse.
【作者單位】： 首都醫(yī)科大學(xué)附屬北京朝陽醫(yī)院呼吸與危重癥醫(yī)學(xué)科/北京呼吸疾病研究所;
【分類號(hào)】：R563.9

【參考文獻(xiàn)】

相關(guān)期刊論文 前4條

1 張鐵栓;張國俊;劉東偉;劉章鎖;;慢性阻塞性肺疾病發(fā)生腎損傷風(fēng)險(xiǎn)評(píng)估研究[J];中國實(shí)用內(nèi)科雜志;2013年11期

2 沈劍;錢翠;高航;包勇;;慢性阻塞性肺疾病急性加重期患者血尿酸肌酐比與疾病嚴(yán)重程度相關(guān)性研究[J];中華肺部疾病雜志(電子版);2013年05期

3 柴晶晶;柳濤;蔡柏薔;;慢性阻塞性肺疾病評(píng)估測(cè)試中文版臨床應(yīng)用意義的評(píng)價(jià)[J];中華結(jié)核和呼吸雜志;2011年04期

4 陳杰;張江義;魯翠紅;;布地奈德聯(lián)合沙丁胺醇霧化吸入對(duì)支氣管哮喘急性發(fā)作的療效觀察[J];臨床肺科雜志;2007年10期

【共引文獻(xiàn)】

相關(guān)期刊論文 前10條

1 胡建;李軍;張銳;;五水頭孢唑林鈉對(duì)急性期老年COPD患者的療效及安全性[J];河北醫(yī)藥;2017年17期

2 李世紅;張黎明;龐寶森;林俊嶺;馬迎民;;腎損傷對(duì)慢性阻塞性肺疾病急性加重及住院的影響[J];重慶醫(yī)學(xué);2017年21期

3 呂翠霞;;支氣管哮喘應(yīng)用布地奈德和沙丁胺醇霧化吸入聯(lián)合治療臨床對(duì)照分析[J];中國實(shí)用醫(yī)藥;2017年21期

4 邢麗艷;;沙丁胺醇聯(lián)合布地奈德應(yīng)用于支氣管哮喘急性發(fā)作治療效果研究[J];中國現(xiàn)代藥物應(yīng)用;2017年14期

5 楊懷宇;石江濤;;雙肺同期大容量肺泡灌洗治療153例塵肺患者[J];重慶醫(yī)學(xué);2017年19期

6 薛彥寧;;不同劑量辛伐他汀治療慢性阻塞性肺疾病的療效、安全性及對(duì)肺功能影響[J];藥物評(píng)價(jià)研究;2017年07期

7 劉冬;許西琳;辛雯艷;蔣雪龍;魯?shù)聅，

本文編號(hào)：1806861