本文選題：肺通氣功能 + 慢性阻塞性肺疾病��； 參考：《南京醫(yī)科大學(xué)學(xué)報(bào)(自然科學(xué)版)》2014年02期

【摘要】：目的:探討脈沖振蕩技術(shù)(IOS)結(jié)合支氣管舒張?jiān)囼?yàn)(BDT)在老年慢性阻塞性肺疾病(COPD)中的應(yīng)用價(jià)值。方法:選擇55例老年穩(wěn)定期COPD患者進(jìn)行支氣管舒張?jiān)囼?yàn),比較用藥前后常規(guī)肺功能與IOS測定結(jié)果。結(jié)果:BDT用藥后的用力肺活量占預(yù)計(jì)值百分比(FVC%pred)、1秒鐘用力呼氣容積占預(yù)計(jì)值百分比(FEV1%pred)、呼出肺活量中間50%時(shí)的平均用力呼氣流量占預(yù)計(jì)值百分比(FEF25%~75%pred)、呼出肺活量50%時(shí)的用力呼氣流量占預(yù)計(jì)值百分比(FEF50%pred)、呼出肺活量75%時(shí)的用力呼氣流量占預(yù)計(jì)值百分比(FEF75%pred)結(jié)果均明顯高于用藥前,差異有統(tǒng)計(jì)學(xué)意義;BDT用藥后患者IOS各參數(shù)均明顯低于對照組,差異有統(tǒng)計(jì)學(xué)意義;氣道總阻力改善率(R5Chg)與1秒鐘用力呼氣容積改善率(FEV1Chg)呈負(fù)相關(guān);低頻電抗面積改善率(AXChg)與用力肺活量改善率(FVCChg)、FEV1Chg、呈正相關(guān);周邊氣道粘性阻力改善率(R5~20Chg)與呼出肺活量50%時(shí)的用力呼氣流量改善率(FEF50Chg)呈負(fù)相關(guān)。結(jié)論:IOS有可能成為老年COPD患者行BDT時(shí)肺通氣功能檢查的必要補(bǔ)充手段;BDT可用于指導(dǎo)老年COPD患者支氣管擴(kuò)張藥的選擇及療效評定。
[Abstract]:Objective: to investigate the application value of pulsed oscillatory technique (IOS) combined with bronchodiastolic test (BDTT) in elderly patients with chronic obstructive pulmonary disease (COPD). Methods: bronchodiastolic test was performed in 55 elderly patients with stable COPD. The results of routine lung function and IOS were compared before and after treatment. Results the percentage of forced vital capacity (RVV) to the predicted value after the administration of FVCpredt and the percentage of forced expiratory volume in one second as a percentage of the predicted value FEV1predr were compared with that of FEV1 predder, and the mean forced expiratory flow (FFEF) at 50 in the middle of vital capacity as a percentage of the predicted value was compared with that of FEF25 / 75predn, and the vital capacity at 50 minutes after exhalation. The percentage of forced expiratory flow to predicted value and the percentage of forced expiratory flow to predicted value when exhaling vital capacity 75 were significantly higher than those before medication. The IOS parameters were significantly lower than those in the control group, and the improvement rate of total airway resistance (R5Chg) was negatively correlated with the improvement rate of forced expiratory volume in 1 second and FEV1Chg. The improvement rate of low frequency reactance area (AXChg) was positively correlated with the improvement rate of forced vital capacity (FVC) and FEV1Chg, and the improvement rate of peripheral airway viscosity resistance (R520Chg) was negatively correlated with the improvement rate of forced expiratory flow (FEF50Chg) at the time of exhaling vital capacity (50%). Conclusion\\\% iOS\\\
【作者單位】： 南京醫(yī)科大學(xué)第一附屬醫(yī)院老年呼吸科;
【基金】：江蘇省高校優(yōu)勢學(xué)科建設(shè)工程(JX10231801)
【分類號】：R563.9

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 鄒春英;沈冬云;王曉蓮;盧妙;李燕;;脈沖振蕩技術(shù)在老年慢性阻塞性肺疾病診斷中的應(yīng)用[J];江蘇醫(yī)藥;2012年23期

【二級參考文獻(xiàn)】

相關(guān)期刊論文 前4條

1 王玉;李曙芳;李海峰;冷靜;;脈沖震蕩法對慢性阻塞性肺疾病患者氣道阻力的測定[J];臨床肺科雜志;2006年05期

2 蔣國華;江雪紅;魏玉萍;;呼吸阻抗測定在慢性阻塞性肺疾病中的應(yīng)用[J];臨床肺科雜志;2010年02期

3 張帥;張虹霞;;慢性阻塞性肺疾病小氣道常規(guī)肺功能與脈沖振蕩法相關(guān)性分析[J];臨床肺科雜志;2011年04期

4 ;慢性阻塞性肺疾病診療規(guī)范(2011年版)[J];中國醫(yī)學(xué)前沿雜志(電子版);2012年01期

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 程一鋒;鄭國毅;嚴(yán)紹南;;吉諾通治療慢性阻塞性肺疾病療效觀察[J];現(xiàn)代中西醫(yī)結(jié)合雜志;2008年01期

2 劉志遠(yuǎn);戎軍;;68例慢性阻塞性肺疾病急性加重期肺通氣功能觀察[J];中國社區(qū)醫(yī)師(醫(yī)學(xué)專業(yè));2010年13期

3 主父瑤;朱益敏;;舒利迭治療中重度慢性阻塞性肺疾病24例[J];河南中醫(yī);2011年01期

4 李U，

本文編號：1779756