本文選題：新疆 + 和田地區(qū)�。� 參考：《新疆醫(yī)科大學(xué)》2015年碩士論文

【摘要】：目的:通過抽取新疆和田地區(qū)洛浦、墨玉、和田3個縣60歲以上維吾爾族老年人行肺功能檢測,分析肺功能與性別、年齡、體重、吸煙、喝酒、營養(yǎng)相關(guān)性,探討影響肺功能常見危險因素,衰老與肺功能相關(guān)性,COPD導(dǎo)致肺功能改變的特點及新疆和田地區(qū)60歲以上維吾爾族老年人肺功能特點。方法:選取2009年4月-6月對新疆和田地區(qū)洛浦、墨玉及和田3個縣農(nóng)村526名完成肺功能檢測的60歲以上維吾爾族老年人為研究對象,納入280例資料完整、符合要求的研究對象,分為COPD組與正常組,同時又將兩組再分為60-、71-、81-、91-四個年齡段。檢測所有研究對象的一般資料,包括年齡、性別、身高、體重、吸煙、喝酒、營養(yǎng)狀況及反應(yīng)肺功能各項指標(biāo),統(tǒng)計被檢者肺功能障礙及肺部疾病情況,分析正常組及COPD組肺功能特點及危險因素。結(jié)果:1、男性老年人肺功能各項指標(biāo)均差于女性老年人,比較有統(tǒng)計學(xué)意義(P0.05)。2、隨著年齡增長肺功能各項指標(biāo)逐漸下降,比較有統(tǒng)計學(xué)意義(P0.05)。3、體重過低、超重、肥胖者肺功能各項指標(biāo)明顯低于正常體重者,比較有統(tǒng)計學(xué)意義(P0.05)。4、吸煙者肺功能各項指標(biāo)明顯低于不吸煙者,比較有統(tǒng)計學(xué)意義(P0.05)。5、喝酒者和不喝酒者肺功能各項指標(biāo)比較無明顯差異,比較無統(tǒng)計學(xué)意義(P0.05)。6、營養(yǎng)缺乏、營養(yǎng)過剩者肺功能各項指標(biāo)低于營養(yǎng)適宜者,比較有統(tǒng)計學(xué)意義(P0.05)。7、性別、年齡、體重、營養(yǎng)、吸煙為影響肺功能危險因素。8、肺換氣功能障者VC、RV、FRL、TLC、VE、FVC及FEF25均降低;動脈血氣異常者TLC、VE、VC、FVC、FEV1/FVC值均降低;運動功能下降者RV、VE增加,VC、MVV、FVC、FEV1、FEF25各值均降低;睡眠障礙者RV、TV、TLC、VE、FVC各值均降低。9、隨著年齡增長,COPD患者者及健康人肺功能各項指標(biāo)均明顯下降;COPD患者肺功能各項指標(biāo)下降較健康人顯著,比較有統(tǒng)計學(xué)意義(P0.05)。10、體重指數(shù)、皮下厚度為COPD患者危險因素。11、COPD患者隨著年齡增加,肺功能指標(biāo)逐漸降低,比較有統(tǒng)計學(xué)意義(P0.05)。12、隨著年齡增加,健康人肺功能各指標(biāo)逐漸降低,比較有統(tǒng)計學(xué)意義(P0.05)。13、COPD組患者肺功能各項指標(biāo)明顯差于非COPD者,兩組比較有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:1、男性老年人肺功能較女性老年人差;隨著年齡增長肺功能逐漸下降;體重指數(shù)為影響肺功能相關(guān)因素,體重過輕、超重、肥胖者肺功能均低于體重正常者;吸煙可導(dǎo)致肺功能顯著下降;營養(yǎng)缺乏、營養(yǎng)過剩者肺功能同樣較營養(yǎng)正常者;喝酒對肺功能影響較小或無明顯影響。2、新疆和田地區(qū)60歲以上維吾爾族老年人肺功能情況同全國肺功能標(biāo)準水平相似,肺功能障礙及相關(guān)肺部疾病發(fā)生情況高于正常范圍。3、肺功能障礙及肺部疾病反應(yīng)出肺功能指標(biāo)有部分規(guī)律性,可進一步研究通過肺功能各項異常指標(biāo)對肺部功能障礙及肺疾病做出輔助診斷。4、隨著年齡增長,老年患者肺功能逐漸降低,COPD患者降低程度較健康人明顯,體重指數(shù)、皮下厚度可導(dǎo)致COPD發(fā)生率增高。
[Abstract]:Objective: to study the correlation between lung function and sex, age, body weight, smoking, drinking alcohol and nutrition in Uygur people over 60 years old in three counties of Hotan, Xinjiang.To explore the common risk factors affecting lung function, the correlation between aging and pulmonary function and the characteristics of pulmonary function changes caused by COPD and the lung function of Uygur people over 60 years old in Hotan area, Xinjiang.Methods: from April to June 2009, 526 Uygur aged over 60 years old from Luopu, Moyu and Hotan counties in Hetian area of Xinjiang were selected as the study objects. 280 cases were included in the study.The patients were divided into COPD group and normal group.The general data of all subjects, including age, sex, height, weight, smoking, alcohol consumption, nutritional status and pulmonary function, were measured.Pulmonary function and risk factors were analyzed in normal group and COPD group.Results the mean value of lung function in male was lower than that in female, and there was significant difference between male and female. With the increase of age, the indexes of lung function decreased gradually, and there was significant difference between male and female, the weight was too low, the weight was too low, and the weight was overweight.The indexes of pulmonary function in obese patients were significantly lower than those of normal body weight (P < 0.05), and the indexes of pulmonary function in smokers were significantly lower than those in non-smokers.There was no significant difference in pulmonary function indexes between drinkers and non-drinkers. There was no significant difference between the indexes of lung function between drinkers and non-drinkers, and there was no significant difference between the indexes of lung function between drinkers and non-drinkers. The indexes of pulmonary function in patients with nutritional overnourishment were lower than those with proper nutrition.Sex, age, body weight, nutrition and smoking were the risk factors of pulmonary function. The risk factors of pulmonary function were decreased in patients with pulmonary ventilation dysfunction, but decreased in patients with pulmonary ventilation dysfunction, and in patients with abnormal arterial blood gas, the values of FEV / FEV1 / FVC were decreased in patients with abnormal arterial blood gas.In the patients with motor dysfunction, the values of RVV VE increased and the values of FEV1 / FEF25 decreased, while in the patients with sleep disorders, the FVC values of RVV TVT TLCV VE decreased by 0.9, and the pulmonary function indexes of COPD patients and healthy persons decreased significantly with the age increase, and the pulmonary function indexes of COPD patients decreased more significantly than those of healthy people.There was significant difference between the two groups (P 0.05. 10, body mass index, subcutaneous thickness was the risk factor of COPD patients.) the pulmonary function index decreased with age, and the lung function index decreased gradually with the increase of age, compared with that of P0.05. 12, with the increase of age, the pulmonary function of healthy people decreased gradually.The indexes of pulmonary function in COPD group were significantly worse than those in non-COPD group, and there was significant difference between the two groups.Conclusion the lung function of male elderly is worse than that of female, and the lung function decreases gradually with the increase of age, the body mass index is the related factor of lung function, the weight is too light, overweight and obesity are lower than those with normal body weight, the lung function of male is lower than that of female.Smoking resulted in a significant decline in pulmonary function, nutrition deficiency, and nutritional overnourishment in patients with pulmonary function were also more than those with normal nutrition.Alcohol drinking had little or no obvious effect on lung function. The pulmonary function of Uygur people over 60 years old in Hotan area of Xinjiang was similar to the level of national lung function standard.The incidence of pulmonary dysfunction and related pulmonary diseases was higher than that of normal range of .3.Pulmonary dysfunction and pulmonary diseases reflected some regularity of pulmonary function.It is possible to further study the auxiliary diagnosis of pulmonary dysfunction and lung diseases by various abnormal indexes of pulmonary function. With the age, the lung function of the elderly patients gradually decreased than that of the healthy people, the degree of reduction of COPD patients was more obvious than that of the healthy people, and the body mass index (BMI) was higher in the elderly patients.Subcutaneous thickness can lead to an increased incidence of COPD.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R563.9
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本文編號：1769613