發(fā)布時間：2018-04-12 18:25

  本文選題：社區(qū)獲得性肺炎 + BALF��； 參考：《福建醫(yī)科大學》2013年碩士論文

【摘要】：目的：統(tǒng)計2012年本地區(qū)社區(qū)獲得性肺炎（CAP）住院患者中致病菌的構(gòu)成比，，常見致病菌的耐藥情況，為經(jīng)驗治療提供依據(jù)。 方法：以回顧性分析研究方法，調(diào)閱福州總醫(yī)院2012年所有確診為社區(qū)獲得性肺炎，入院48小時內(nèi)行纖支鏡檢查的患者。收集患者的基本資料、細菌種類、藥敏結(jié)果進行統(tǒng)計分析。 結(jié)果：確診肺炎患者209例，其中男性157例，女性52例，年齡16~92歲，需住院的肺炎患者發(fā)病年齡段以50~80歲最為多見，吸煙者112例。革蘭氏染色檢出率為45.5%，陰性菌34%，陽性菌10.5%，真菌1%，細菌培養(yǎng)檢出率為34.9%，肺炎克雷伯桿菌16例，銅綠假單胞菌11例，大腸埃希菌8例，真菌（白色念珠菌）7例，肺炎鏈球菌3例，流感嗜血桿菌1例，溶血葡萄球菌6例。主要革蘭氏陰性菌耐藥率最高和最低的分別是氨芐西林92.31%，哌拉西林/他唑巴坦15.38%。 結(jié)論：BALF革蘭氏染色及細菌培養(yǎng)檢出率分別為45.5%和34.9%，較其他文獻報告的痰培養(yǎng)檢出率高，但仍有大部分未檢出。伴有基礎(chǔ)疾病的CAP致病菌以陰性菌為主，肺炎鏈球菌、流感嗜血桿菌、卡他莫拉菌為苛養(yǎng)菌，較難培養(yǎng)。
[Abstract]:Objective: to analyze the proportion of pathogenic bacteria and drug resistance of common pathogens in the inpatients with community acquired pneumonia (CAP) in our area in 2012, and to provide evidence for empirical treatment.Methods: all the patients diagnosed as community-acquired pneumonia in Fuzhou General Hospital in 2012 were examined with fiberoptic bronchoscopy within 48 hours after admission.Collect the basic data of patients, bacteria types, drug sensitivity results for statistical analysis.Results: 209 cases of pneumonia were diagnosed, among them 157 cases were male, 52 cases were female, the age of pneumonia was 16 ~ 92 years old. The most common age of pneumonia patients in hospital was 50 ~ 80 years old, 112 cases of smokers.One case was Haemophilus influenzae and 6 cases were Staphylococcus haemolyticus.The highest and lowest resistance rates of major gram-negative bacteria were ampicillin 92.31 and piperacillin / tazobactam 15.38 respectively.Conclusion the detectable rates of Gram-BALF Gram staining and bacterial culture were 45.5% and 34.9% respectively, which were higher than those reported in other literatures, but most of them were not detected.The main pathogenic bacteria of CAP with basic diseases were negative bacteria, Streptococcus pneumoniae, Haemophilus influenzae and Cartamora were caustic bacteria, which were difficult to culture.
【學位授予單位】：福建醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2013
【分類號】：R563.1

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本文編號：1740905