本文選題：慢性阻塞性肺疾病 + 肺動脈高壓　； 參考：《皖南醫(yī)學院》2017年碩士論文

【摘要】：目的:通過回顧性分析來探討心室內(nèi)徑比與COPD患者合并PH的相關(guān)性,并檢測CRP、BNP、血氣分析、RDW等指標與其相關(guān)性,從而更快速便捷地評估COPD合并PH,從而更好地干預治療、改善預后和增加生存率。方法:本研究收集2015年3月份到2016年12月份期間入住皖南醫(yī)學院第一附屬醫(yī)院呼吸內(nèi)科住院治療的80位COPD患者,通過超聲心動圖篩選COPD合并PH并觀察其心室比(RV/LV)、BNP、血氣分析、CRP、D-D、RDW等與PH的相關(guān)性。結(jié)果:各種指標中,RV/LV、BNP、D-二聚體、CRP、RDW、PCO2在COPD繼發(fā)PH比COPD單純組組高,且PH升高中,COPD繼發(fā)中重度PH較輕度偏高,兩兩組無統(tǒng)計學差異(F值分別為22.94、20.29、13.51、28.74、17.69、12.73,P均0.01);上述指標經(jīng)過Pearson相關(guān)分析表明與PH具有正相關(guān)性(r分別為0.57、0.59、0.46、0.63、0.51、0.48,P均0.01).同時PO2表現(xiàn)為COPD繼發(fā)PH較COPD患者偏低,COPD繼發(fā)中重度較輕度組更低,兩兩組無統(tǒng)計學差異(F=27.63),PO2與PH具有負相關(guān)(r=-0.61,P0.01)。結(jié)論:RV/LV、BNP、D-二聚體、CRP、RDW、PCO2與PH呈正相關(guān),PO2與PH呈負相關(guān),以上指標在一定程度上可以預測評估PH的嚴重程度。
[Abstract]:Objective: to investigate the correlation between ventricular diameter ratio and PH in patients with COPD by retrospective analysis, and to detect the correlation between COPD and RDW, so as to evaluate COPD with PH more quickly and conveniently, and to better intervene in treatment.Improve prognosis and increase survival rate.Methods: from March 2015 to December 2016, 80 COPD patients admitted to Department of Respiratory Medicine, the first affiliated Hospital of Southern Anhui Medical College, were collected.COPD combined with PH was screened by echocardiography and its ventricular ratio of RV / LVN was observed. Blood gas analysis was used to analyze the correlation between RV / RDW and PH.Results: the secondary PH of COPD group was higher than that of COPD group, and the secondary PH of RV / LVN BNP-dimer group was higher than that of COPD group, and the secondary PH of RV / LVN BNP-dimer was higher than that of mild PH.At the same time, PO2 showed that the secondary PH of COPD was lower than that of COPD. The secondary PH of COPD was lower than that of mild group. There was no statistical difference between the two groups.Conclusion there is a positive correlation between RDWCO _ 2 and PH and a negative correlation between PH and PCO _ 2. The above indexes can predict the severity of PH to some extent.
【學位授予單位】：皖南醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R563.9;R544.1

【參考文獻】

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本文編號：1737152