發(fā)布時間：2018-03-16 04:03

  本文選題：吸氣峰流量　切入點：慢性阻塞性肺疾病　出處：《中國實用內(nèi)科雜志》2014年S1期 　論文類型：期刊論文

【摘要】：目的探討不同嚴(yán)重程度的慢性阻塞性肺疾病(COPD)患者在不同干粉吸入器阻力狀態(tài)下的吸氣能力。方法 54例中老年COPD患者納入研究,年齡(67.7±8.4)歲,采用In-Check DIAL吸氣峰流量儀,測定模擬準(zhǔn)納器阻力狀態(tài)下的吸氣峰流量(PIF-Diskus,PIF-D)以及模擬都保阻力狀態(tài)下的吸氣峰流量(PIF-Turbuhaler,PIF-T),同時測定呼氣峰流量(PEF)以及舒張后肺功能。結(jié)果 1例(1.9%)COPD患者未能達到Diskus的最低吸氣流量(30L/min)要求,12例(22.2%)未能達到Turbuhaler的最低吸氣流量(60L/min)要求,兩組間有統(tǒng)計差異(χ2=10.581,P=0.001)。對于PIF-D,7.1%的Ⅳ級COPD患者低于理想吸氣流量,Ⅱ級和Ⅲ級的PIF-D均達到理想吸氣流量或以上,不同級別COPD患者的PIF-D分級分布情況無統(tǒng)計學(xué)差異(χ2=5.665,P=0.226)。對于PIF-T,Ⅱ級、Ⅲ級、Ⅳ級的COPD患者的比例為11.8%、26.1%、28.6%,不同級別COPD患者的PIF-T分級分布情況無統(tǒng)計學(xué)差異(χ2=3.222,P=0.521)。經(jīng)直線回歸分析表明,COPD患者PEF測定值與PIF-D和PIF-T測定值均呈正相關(guān)(r值分別為0.584和0.478,P均=0.01)。結(jié)論通過COPD患者的疾病嚴(yán)重程度,無法判斷患者是否真正有效地吸入藥物。In-Check DIAL吸氣峰流量儀可測定COPD患者在不同吸入器阻力狀態(tài)下吸氣流量,臨床醫(yī)生可根據(jù)患者的測定結(jié)果來為患者選用不同的吸入器,并開具合理的藥物處方,適于在臨床上推廣應(yīng)用。
[Abstract]:Objective to investigate the inspiratory capacity of patients with different severity of chronic obstructive pulmonary disease (COPD) under different resistance states of dry powder inhalers. Methods 54 middle-aged and aged COPD patients, aged 67.7 鹵8.4 years, were enrolled in the study with In-Check DIAL inspiratory peak flow meter. The inspiratory peak flow (PIF-Diskusus PIF-D-) and the peak inspiratory flow (PIF-Turbuhalerus PIF-TN) were measured at the same time, and the peak expiratory flow (PEF) and the pulmonary function after diastolic were measured. Results one patient with PIF-Diskusus PIF-D- was not able to achieve Diskus. The minimum inspiratory flow (30 L / min) required 12 cases (22. 2) did not meet the minimum inspiratory flow (60 L / min) requirement of Turbuhaler. There was statistical difference between the two groups (蠂 2 + 10.581%). For grade 鈪，

本文編號：1618221