發(fā)布時間：2018-03-10 03:15

  本文選題：真菌感染　切入點：曲霉菌　出處：《復旦大學》2013年碩士論文　論文類型：學位論文

【摘要】：目的：探討原發(fā)性肺部真菌感染的特征性CT表現(xiàn),以提高診斷和鑒別診斷水平。 方法：收集2004年到2012年的18例原發(fā)性肺真菌感染病例,復習其CT表現(xiàn)和臨床資料,分析和總結(jié)原發(fā)性真菌感染的CT特征性表現(xiàn)。全部病例均經(jīng)臨床治療性診斷、手術病理證實或血清學檢查確診。結(jié)果：18例原發(fā)性肺部真菌病患者CT均表現(xiàn)為軟組織密度結(jié)節(jié)(15/18)或腫塊(3/18)。經(jīng)病理及血清學檢查,12例為曲霉菌感染,3例為新型隱球菌感染,3例為球孢子菌。曲霉菌感染的CT表現(xiàn)：類圓形病灶(12/12)、分葉征及毛刺征(6/12)、支氣管穿過征(3/12)、空氣新月征(6/12)、兩肺門及縱隔腫大淋巴結(jié)(3/12),6例CT增強掃描3例無強化,3例輕度強化。新型隱球菌感染的CT表現(xiàn)：均為菜花狀病灶,可見分葉及毛刺征,內(nèi)見鈣化灶,兩肺門及縱隔未見腫大淋巴結(jié),CT增強掃描均表現(xiàn)部分強化。球孢子菌感染的CT表現(xiàn)：均為不規(guī)則病灶,周圍可見暈征,兩肺門及縱隔淋巴結(jié)腫大。 結(jié)論：原發(fā)性肺部真菌病CT多表現(xiàn)為結(jié)節(jié)或腫塊,增強掃描不強化或輕度強化,“空氣新月征”是曲霉菌感染的特征,新型隱球菌病灶呈“菜花樣”且伴鈣化,“暈征”在球孢子菌病多見。
[Abstract]:Objective: to investigate the CT features of primary pulmonary fungal infection in order to improve the diagnostic and differential diagnosis. Methods: eighteen cases of primary pulmonary fungal infection from 2004 to 2012 were collected, their CT manifestations and clinical data were reviewed, and the CT features of primary fungal infection were analyzed and summarized. Results the CT findings of 18 cases of primary pulmonary mycosis were as follows: soft tissue density nodule 15 / 18) or mass 3 / 18. Pathological and serological examination showed that 12 cases were aspergillus infection and 3 cases were new cryptospheres. The CT findings of Aspergillus infection were as follows: round lesions 12 / 12, lobular and hairy signs 6 / 12, bronchial crossing sign 3 / 12, air crescent sign 6 / 12, enlarged lymph nodes of both hilum and mediastinum in 6 / 12, CT enhancement in 3 cases. The CT findings of Cryptococcus neoformans infection were all cauliflower lesions. Lobular and burr signs were seen, calcified foci were seen inside, CT enhancement was partially enhanced in both hilar and mediastinal lymph nodes. Ct manifestations of globosporidium infection were irregular lesions and halo signs around them. Enlargement of both hilar and mediastinal lymph nodes. Conclusion: the CT features of primary pulmonary mycosis are nodule or mass, no or slight enhancement on enhanced CT scan, and "air crescent sign" is the characteristic of aspergillus infection. The focus of Cryptococcus neoformans is "vegetable pattern" with calcification, and halo sign is more common in globocystis.
【學位授予單位】：復旦大學
【學位級別】：碩士
【學位授予年份】：2013
【分類號】：R519;R816.41

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