顱腦術后患者肺部感染的危險因素及干預效果研究
發(fā)布時間:2018-02-20 20:13
本文關鍵詞: 顱腦手術 肺部感染 危險因素 目標監(jiān)測 干預措施 出處:《中華醫(yī)院感染學雜志》2017年01期 論文類型:期刊論文
【摘要】:目的分析顱腦術后肺部感染的危險因素,探討其干預效果,為臨床診治提供參考依據。方法選擇2013年1月-2014年12月125例開顱手術患者為對照組,另選2015年1-12月64例開顱手術患者為觀察組,針對高危因素進行目標監(jiān)測和干預,采用χ2檢驗比較兩組術后并發(fā)肺部感染、限制級抗菌藥物的使用、住院時間、病死率的情況。結果單因素分析顯示,年齡≥65歲、GCS評分≤7分、預防性應用抗菌藥、有吸煙史、ASA評級Ⅱ級、白蛋白水平30g/L、手術時間≥3h、術前血糖8mmol/L、伴有意識障礙、合并基礎疾病、呼吸機輔助通氣是術后肺部感染的影響因素(P0.05);多因素logistic回歸分析顯示,GCS評分≤7分、預防性應用抗菌藥、有吸煙史、白蛋白水平30g/L、術前血糖8mmol/L、伴有意識障礙、呼吸機輔助通氣為術后肺部感染的獨立危險因素(P0.05);干預后術后肺部感染率為23.44%,使用特殊級抗菌藥6例,平均住院時間(12.00±4.28)d,病死率為7.81%,均較對照組減少(P0.05)。結論顱腦術后肺部感染發(fā)生的相關危險因素較多,臨床根據這些危險因素采取目標監(jiān)測和干預,能降低術后肺部感染率及病死率,減少特殊級抗菌藥的使用,縮短住院時間,是預防顱腦術后肺部感染的有效措施之一。
[Abstract]:Objective to analyze the risk factors of pulmonary infection after craniocerebral surgery, to explore the effect of intervention, and to provide reference for clinical diagnosis and treatment. Methods 125 patients undergoing craniotomy from January 2013 to December 2014 were selected as control group. In addition, 64 patients undergoing craniotomy from January to December of 2015 were selected as observation group. The objective monitoring and intervention were carried out for high risk factors. 蠂 2 test was used to compare the postoperative pulmonary infection, the use of restricted antibiotics, and the length of stay in hospital between the two groups. Results univariate analysis showed that age 鈮,
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