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肺部感染患者支氣管肺泡灌洗液培養(yǎng)非發(fā)酵菌分析研究

發(fā)布時(shí)間:2018-01-06 01:36

  本文關(guān)鍵詞:肺部感染患者支氣管肺泡灌洗液培養(yǎng)非發(fā)酵菌分析研究 出處:《中華醫(yī)院感染學(xué)雜志》2016年08期  論文類型:期刊論文


  更多相關(guān)文章: 肺部感染 支氣管肺泡灌洗液 培養(yǎng) 非發(fā)酵菌


【摘要】:目的探討肺部感染患者送檢支氣管肺泡灌洗液培養(yǎng)的非發(fā)酵菌感染狀況,為肺部感染患者的臨床診治和預(yù)防提供參考依據(jù)。方法以2012年12月-2014年12月醫(yī)院臨床收治疑似肺部感染患者554例為研究對(duì)象,采用支氣管肺泡灌洗液培養(yǎng)的方式對(duì)患者分泌物進(jìn)行培養(yǎng)和檢測(cè),調(diào)查其病原菌檢出率、非發(fā)酵菌的分布和耐藥性,數(shù)據(jù)采用SPSS 19.0軟件進(jìn)行統(tǒng)計(jì)分析。結(jié)果 554例患者的分泌物中共分離病原菌198株,檢出率為39.40%;198株病原菌中非發(fā)酵菌94株占47.47%;銅綠假單胞菌、鮑氏不動(dòng)桿菌、嗜麥芽寡養(yǎng)單胞菌對(duì)亞胺培南、美羅培南、多黏菌素B耐藥率較低,均35.00%。結(jié)論肺部感染患者的非發(fā)酵菌的臨床檢出率和耐藥性均較高,臨床工作者應(yīng)按照藥敏結(jié)果為指導(dǎo)科學(xué)合理用藥,從而有效的降低肺部感染發(fā)生率。
[Abstract]:Objective to investigate the infection status of non fermentative bacteria from bronchoalveolar lavage fluid culture of patients with pulmonary infection, and provide reference for clinical diagnosis and treatment and prevention of pulmonary infection in patients. Methods in December 2012 -2014 year in December admitted to hospital clinical suspected pulmonary infection in 554 patients as the research object, using bronchoalveolar lavage fluid culture method for culturing and testing with the investigation of secretions, pathogen detection rate, distribution and drug resistance of non fermentative bacteria, SPSS 19 software was used for statistical analysis. Results 554 cases of patients with the secretion of isolated 198 strains of pathogenic bacteria, the detection rate was 39.40%; 198 strains of pathogenic bacteria in 94 strains of non fermentative bacilli accounted for 47.47%; Pseudomonas aeruginosa, abalone Acinetobacter and Stenotrophomonas maltophilia to imipenem, meropenem, polymyxin B resistance rates were 35.00%. the conclusion of non fermentation bacteria of pulmonary infection in patients with clinical The bed detection rate and drug resistance are all high. The clinical workers should guide scientific and rational drug use according to the results of drug sensitivity, which can effectively reduce the incidence of pulmonary infection.

【作者單位】: 安陽市人民醫(yī)院檢驗(yàn)科;
【基金】:河南省杰出人才創(chuàng)新基金資助項(xiàng)目(0823092311)
【分類號(hào)】:R563.1
【正文快照】: 非發(fā)酵菌已經(jīng)成為感染致病菌中的重要病原菌,在臨床實(shí)踐的過程中,針對(duì)病原菌的臨床檢驗(yàn)對(duì)于疾病診治具有重要臨床指導(dǎo)意義。但是,在對(duì)患者痰液標(biāo)本進(jìn)行送檢的過程中,傳統(tǒng)常規(guī)的方法無法避免口咽菌群對(duì)于標(biāo)本的污染,從而對(duì)臨床檢查結(jié)果產(chǎn)生一定的影響[1]。本研究對(duì)2012年12月-2

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2 韓金霞,張菊英,葛庚芝,司進(jìn),李彬;下呼吸道感染中非發(fā)酵菌耐藥性分析[J];中國(guó)抗感染化療雜志;2004年04期

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4 林s鉅,

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