【摘要】：甘油三酯脂肪酶(ATGL)家族是孕期母體脂質(zhì)代謝的關(guān)鍵酶,通過水解脂蛋白的甘油三酯和磷脂以釋放游離脂肪酸,使母體的脂質(zhì)轉(zhuǎn)運(yùn)給胎兒。多項(xiàng)研究表明,子癇前期(PE)孕婦體內(nèi)多存在脂質(zhì)代謝紊亂,并與ATGL基因表達(dá)異常密切相關(guān)。
[Abstract]:Glycerol lipase (ATGL) family is the key enzyme of maternal lipid metabolism during pregnancy. Free fatty acids are released by hydrolyzing lipoprotein glycerides and phospholipids to transport maternal lipids to fetuses. Many studies have shown that most of the pregnant women with preeclampsia (PE) have disorder of lipid metabolism, which is closely related to the abnormal expression of ATGL gene.
【作者單位】： 上海交通大學(xué)醫(yī)學(xué)院附屬國際和平婦幼保健院;
【基金】：國家自然科學(xué)基金
【分類號(hào)】：R714.244
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本文編號(hào)：2525037