【摘要】：目的:探討八珍湯加減聯(lián)合抗菌藥物治療氣血兩虛型產(chǎn)后發(fā)熱的臨床療效及安全性。方法:選取我院2014年12月-2016年6月收治的氣血兩虛型產(chǎn)后發(fā)熱患者94例,按隨機(jī)數(shù)字表法分為對照組和觀察組,各47例。對照組患者給予注射用頭孢唑林鈉3 g加入氯化鈉注射液250 m L中,ivgtt,bid;若連續(xù)2 d體溫未下降,則給予注射用阿奇霉素250 mg加入氯化鈉注射液250m L中,ivgtt,bid;體溫超過38.5℃者肌內(nèi)注射復(fù)方氨林巴比妥注射液2 m L。觀察組患者在對照組基礎(chǔ)上給予八珍湯加減治療。兩組患者療程均為5 d。比較兩組患者臨床療效及治療前后白細(xì)胞計數(shù)、血漿C反應(yīng)蛋白(CRP)、血漿黏度、血漿纖維蛋白原(Fib)水平,觀察兩組患者退熱時間、住院時間及不良反應(yīng)發(fā)生情況。結(jié)果:觀察組患者總有效率為95.75%,顯著高于對照組的78.72%,差異有統(tǒng)計學(xué)意義(P0.05)。治療前,兩組患者白細(xì)胞計數(shù)、CRP、血漿黏度、Fib水平比較,差異均無統(tǒng)計學(xué)意義(P0.05);治療后,兩組患者白細(xì)胞計數(shù)、CRP、血漿黏度、Fib水平均顯著下降,且觀察組水平顯著低于對照組,差異均有統(tǒng)計學(xué)意義(P0.05)。觀察組患者退熱時間和住院時間均短于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。觀察組患者不良反應(yīng)發(fā)生率為6.38%,顯著低于對照組的23.40%,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:八珍湯加減聯(lián)合抗菌藥物治療氣血兩虛型產(chǎn)后發(fā)熱療效顯著,能明顯改善患者炎癥狀態(tài)和血漿黏度,加快患者退熱,且安全性高。
[Abstract]:Objective: to investigate the clinical efficacy and safety of Bazhen decoction combined with antibiotics in the treatment of postpartum fever with deficiency of qi and blood. Methods: from December 2014 to June 2016, 94 patients with postpartum fever with deficiency of both qi and blood were randomly divided into control group (n = 47) and observation group (n = 47). The control group was given cefazolin sodium 3 g and sodium chloride injection 250 mL. If the body temperature of ivgtt,bid; did not decrease for 2 days, azithromycin 250 mg and sodium chloride injection 250 mL were given intramuscular injection of compound aminobarbital injection 2 mL if the body temperature of cefazolin sodium for injection exceeded 38.5 鈩，

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