早期宮頸癌保留生育功能核心指標(biāo)的臨床研究
發(fā)布時(shí)間：2019-06-29 11:29
【摘要】：目的本研究探討了早期宮頸癌患者保留生育功能的影響因素及其可行性。 方法本研究選取了133例宮頸癌FIGO分期為I期的患者，回顧性分析其腫瘤浸潤(rùn)深度比例，腫瘤病灶大小以及腫瘤病理類型，深入探討其對(duì)于宮旁浸潤(rùn)，脈管累及，淋巴轉(zhuǎn)移的影響。 結(jié)果①26例Ia1期患者，無(wú)脈管累及；其中2例行盆腔淋巴結(jié)清掃術(shù)，無(wú)淋巴轉(zhuǎn)移。②7例Ia2期患者，均無(wú)宮旁浸潤(rùn)、脈管累及和淋巴轉(zhuǎn)移。③88例Ib1期患者，宮旁浸潤(rùn)10例（11.4%）、脈管累及19例（21.6%）、淋巴轉(zhuǎn)移11例（12.5%）。④12例Ib2期患者，宮旁浸潤(rùn)1例（8.3%）、脈管累及2例（16.7%）、淋巴轉(zhuǎn)移1例（8.3%）。⑤當(dāng)腫瘤浸潤(rùn)深度比例≥1/2時(shí)，更容易發(fā)生轉(zhuǎn)移。⑥當(dāng)腫瘤浸潤(rùn)深度比例≥2/3時(shí)，更容易發(fā)生宮旁浸潤(rùn)及淋巴轉(zhuǎn)移。⑦腫瘤浸潤(rùn)深度比例與脈管累及無(wú)關(guān)，腫瘤的病灶大小與有無(wú)轉(zhuǎn)移無(wú)關(guān)。 結(jié)論宮頸癌Ia1期患者，若無(wú)脈管累及，可行宮頸錐形切除術(shù)；若有脈管累及，需行廣泛子宮頸切除術(shù)，保留生育功能。宮頸癌Ia2期患者，若無(wú)脈管累及，可以選擇廣泛子宮頸切除術(shù)。宮頸癌Ib1期患者，若無(wú)脈管累及，腫瘤最大直徑≤2cm，腫瘤浸潤(rùn)深度比例小于1/2，無(wú)淋巴轉(zhuǎn)移，可行廣泛子宮頸切除術(shù)，，保留生育功能，但術(shù)后需注意密切隨訪。
[Abstract]:Objective to investigate the influencing factors and feasibility of fertility retention in patients with early cervical cancer. Methods in this study, 133 patients with stage I cervical cancer with FIGO stage were analyzed retrospectively. the proportion of tumor invasion depth, the size of tumor focus and the pathological type of tumor were analyzed retrospectively. the effects of tumor invasion, vascular involvement and lymph node metastasis on periuterine invasion, vascular involvement and lymph node metastasis were discussed in detail. Results there were no vascular involvement in 126 patients with Ia1. Pelvic lymph node dissection was performed in 2 cases, no lymph node metastasis. 27 patients with Ia2 stage had no paracymal invasion, vessel involvement and lymphatic metastasis. 388 patients with Ib1 stage, 10 patients with periuterine infiltration, 19 patients with periuterine invasion, 11 patients with lymph node metastasis, 412 patients with Ib2 stage, 1 patient with periuterine invasion, 2 patients with periuterine invasion, 12. 5% patients with Ib2 stage, 1 patient with periuterine infiltration, 2 patients with periuterine invasion, 11 patients with lymph node metastasis, 11 patients with paracircular lymph node involvement, 11 patients with paracymal lymph node metastasis. Lymph node metastasis occurred in 1 case (8.3%). 5 when the ratio of tumor invasion depth 鈮
本文編號(hào)：2507781
[Abstract]:Objective to investigate the influencing factors and feasibility of fertility retention in patients with early cervical cancer. Methods in this study, 133 patients with stage I cervical cancer with FIGO stage were analyzed retrospectively. the proportion of tumor invasion depth, the size of tumor focus and the pathological type of tumor were analyzed retrospectively. the effects of tumor invasion, vascular involvement and lymph node metastasis on periuterine invasion, vascular involvement and lymph node metastasis were discussed in detail. Results there were no vascular involvement in 126 patients with Ia1. Pelvic lymph node dissection was performed in 2 cases, no lymph node metastasis. 27 patients with Ia2 stage had no paracymal invasion, vessel involvement and lymphatic metastasis. 388 patients with Ib1 stage, 10 patients with periuterine infiltration, 19 patients with periuterine invasion, 11 patients with lymph node metastasis, 412 patients with Ib2 stage, 1 patient with periuterine invasion, 2 patients with periuterine invasion, 12. 5% patients with Ib2 stage, 1 patient with periuterine infiltration, 2 patients with periuterine invasion, 11 patients with lymph node metastasis, 11 patients with paracircular lymph node involvement, 11 patients with paracymal lymph node metastasis. Lymph node metastasis occurred in 1 case (8.3%). 5 when the ratio of tumor invasion depth 鈮
本文編號(hào)：2507781
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