【摘要】：目的 :探討妊娠期糖尿病合并子癇前期的相關(guān)因素及妊娠結(jié)局。方法 :選取2015年1—5月在南京市婦幼保健院住院分娩的無合并子癇前期的妊娠期糖尿病單胎孕婦98例為對(duì)照組,妊娠期糖尿病合并子癇前期孕婦68例為研究組。收集兩組孕婦的體重指數(shù)(BMI)、空腹血糖(FBG)、糖化血紅蛋白(Hb A1c)、甘油三酯(TG)、總膽固醇(TC)、尿酸(UA)、乳酸脫氫酶(LDH)、堿性磷酸酶(ALP)進(jìn)行對(duì)比分析。同時(shí)比較兩組的產(chǎn)后出血、剖宮產(chǎn)、早產(chǎn)、胎窘、胎膜早破、產(chǎn)間發(fā)熱、羊水量情況、胎兒宮內(nèi)生長(zhǎng)遲緩(FGR)及巨大兒的發(fā)生率。結(jié)果:1研究組的BMI、FBG、TG、TC、UA均高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);2研究組的產(chǎn)后出血、剖宮產(chǎn)、早產(chǎn)、胎窘、羊水過少、FGR的發(fā)生率高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 :孕婦的體重指數(shù)、空腹血糖控制不理想、血甘油三酯、血膽固醇升高是妊娠期糖尿病合并子癇前期的相關(guān)風(fēng)險(xiǎn)因素,妊娠期糖尿病合并子癇前期將進(jìn)一步增加母兒不良妊娠結(jié)局的發(fā)生。
[Abstract]:Objective: to investigate the related factors and pregnancy outcome of gestational diabetes mellitus complicated with preeclampsia. Methods: 98 pregnant women with gestational diabetes mellitus without preeclampsia and 68 pregnant women with gestational diabetes mellitus complicated with preeclampsia were selected as control group and 68 pregnant women with gestational diabetes mellitus complicated with preeclampsia from January to May 2015 in Nanjing Maternal and Child Health Hospital. Fasting blood glucose (FBG), glycosylated hemoglobin (Hb A1c) and total cholesterol (TC), uric acid (UA), lactic dehydrogenase (LDH), were collected in two groups of pregnant women with body mass index (BMI), fasting blood glucose and glycosylated hemoglobin (Hb A1c). Alkaline phosphatase (ALP) was compared and analyzed. At the same time, the incidence of postpartum hemorrhage, cesarean section, premature delivery, fetal embarrassment, premature rupture of membranes, parturient fever, amniotic fluid volume, fetal growth retardation (FGR) and macrosomia were compared between the two groups. Results: 1the BMI,FBG,TG,TC,UA of the study group was higher than that of the control group, the difference was statistically significant (P 0.05). 2 the incidence of postpartum hemorrhage, cesarean section, premature delivery, fetal embarrassment and oligoamniotic fluid in the study group was significantly higher than that in the control group (P 0.05). Conclusion: the body mass index (BMI) and fasting blood glucose (FBG) of pregnant women are not well controlled, and the increase of serum TG and cholesterol are the risk factors of gestational diabetes mellitus complicated with preeclampsia. Gestational diabetes mellitus complicated with preeclampsia will further increase the occurrence of adverse pregnancy outcomes in mothers and infants.
【作者單位】： 南京醫(yī)科大學(xué)附屬南京婦幼保健院婦產(chǎn)科;
【分類號(hào)】：R714.256;R714.244

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