【摘要】：目的探討母親妊娠期因素和圍生期因素與子女青少年期血壓之間的關系。方法對1993-1995年無錫市建立的出生隊列于2011-2013年(青少年期)進行隨訪,開展問卷調查、身高、體重和血壓的測量,采用醊2檢驗、多元線性回歸分析、多因素二項式回歸等統(tǒng)計方法進行數據分析。結果共隨訪到年齡16~18歲之間的青少年2 256人。調整性別、青少年期年齡、青少年期超重或肥胖、青少年期生活行為因素,將母親妊娠期和圍生期相關變量納入多因素模型,結果顯示:母親產時有妊高癥的對象,青少年期的收縮壓和舒張壓升高,"血壓升高比例"增加(RR=1.54,95%CI:1.26~1.90);隨著出生身長的增加,青少年的收縮壓升高。結論母親產時妊高癥是子女青少年期血壓升高的危險因素,應采取一定的措施,控制妊高癥的發(fā)生。
[Abstract]:Objective to explore the relationship between maternal pregnancy factors and perinatal factors and blood pressure of children in adolescence. Methods the birth cohort established in Wuxi from 1993 to 1995 was followed up from 2011 to 2013. Questionnaire survey was carried out. Height, weight and blood pressure were measured, and multiple linear regression analysis was used to analyze the relationship between birth cohort and height, weight and blood pressure. Multi-factor binomial regression and other statistical methods were used for data analysis. Results A total of 2 256 adolescents aged between 16 and 18 were followed up. Adjusted for gender, adolescence age, adolescent overweight or obesity, adolescent life behavior factors, the related variables of maternal pregnancy and perinatal period were included in the multi-factor model. The results showed that the subjects with pregnancy-induced hypertension (PIH) were the subjects with pregnancy-induced hypertension (PIH) at the time of birth. Systolic and diastolic blood pressure (SBP) and diastolic blood pressure (DBP) increased during adolescence, and the "increased blood pressure ratio" (RR=1.54,95%CI:1.26~1.90) increased. As birth length increases, systolic blood pressure increases in adolescents. Conclusion pregnancy-induced hypertension (PIH) is a risk factor for the increase of blood pressure in young children, and some measures should be taken to control the occurrence of PIH.
【作者單位】： 上海市計劃生育科學研究所/國家衛(wèi)計委計劃生育藥具重點實驗室;新鄉(xiāng)醫(yī)學院公共衛(wèi)生學院流行病與衛(wèi)生統(tǒng)計學教研室;上海中醫(yī)藥大學基礎醫(yī)學院預防醫(yī)學教研室;
【基金】：國家自然科學基金(81072364)
【分類號】：R715.3

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