二甲雙胍對多囊卵巢綜合征胰島素抵抗患者卵巢間質血流影響的三維超聲表現(xiàn)
[Abstract]:Objective to investigate the effect of metformin PCOS-IR on interstitial blood flow in patients with polycystic ovary syndrome (PCOS) with insulin resistance (IR) by using three dimensional power Doppler ultrasound. Methods 40 patients with PCOS-IR and 20 married women with normal ovulation were selected as observation group and control group. The observation group took metformin for 3 cycles. The difference of ovarian interstitial blood flow parameters (VI,FI,VFI), ovarian volume, follicle number and reproductive endocrine index before and after treatment were compared between the observation group and the control group and the observation group. Results compared with the control group, the blood flow parameters of the ovarian stroma in the observation group increased, the number of follicles decreased, the VI,FI,VFI of the interstitial blood flow parameters of the ovary decreased, and the reproductive endocrine LH,LH/FSH,T decreased after 3 months of treatment in the observation group. The difference was statistically significant (P0.05). Ovarian volume decreased, the difference was not statistically significant (P0.05). Conclusion metformin can improve the microcirculation of ovarian stroma in patients with PCOS-IR. Three-dimensional power Doppler ultrasound can provide a quantitative scheme of ovarian hemodynamics for evaluating the therapeutic effect of PCOS, and it has certain clinical value.
【作者單位】: 廣州中醫(yī)藥大學研究生院;廣州中醫(yī)藥大學第一附屬醫(yī)院超聲科;
【分類號】:R711.75
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