絕經(jīng)后子宮內(nèi)膜息肉惡變與代謝綜合征的關(guān)系初探
發(fā)布時間：2018-12-25 13:41
【摘要】：目的探討絕經(jīng)后子宮內(nèi)膜息肉惡變與代謝綜合征的關(guān)系,進而探討其潛在惡變及惡變的危險因素,為代謝綜合征患者的子宮內(nèi)膜息肉的早期診治提供理論依據(jù)。方法分析2006年1月-2013年1月該院婦產(chǎn)科收治的435例經(jīng)宮腔鏡病理確診為子宮內(nèi)膜息肉的患者,依據(jù)病理類型分為良性組(415例)和非典型增生(惡變組)(20例),對兩組臨床資料進行回顧性分析。結(jié)果子宮內(nèi)膜息肉的惡變率4.6%,單因素分析,與子宮內(nèi)膜息肉發(fā)生非典型增生或惡變的相關(guān)因素有體質(zhì)指數(shù)(BMI)、絕經(jīng)年限、絕經(jīng)后陰道流血、子宮內(nèi)膜厚度、腰圍、空腹血糖、血三酰甘油(TG)、血高密度脂蛋白(HDL)(P0.05),多元回歸分析后得出,BMI、腰圍、舒張壓、血TG、血HDL、空腹血糖或確診為糖耐量異常或糖尿病是子宮內(nèi)膜癌合并代謝綜合征的獨立危險因素(P0.05)。結(jié)論患有子宮內(nèi)膜息肉的絕經(jīng)婦女,子宮內(nèi)膜息肉惡變與代謝綜合征關(guān)系密切,建議絕經(jīng)后有代謝綜合征的子宮內(nèi)膜息肉患者,應(yīng)嚴密隨訪,如合并陰道流血、內(nèi)膜厚度≥5 mm,息肉≥8 mm或息肉多發(fā)等高危因素,應(yīng)在宮腔鏡下切除息肉。
[Abstract]:Objective to investigate the relationship between endometrial polyp malignancy and metabolic syndrome after menopause, and to explore its potential malignant change and its risk factors, so as to provide theoretical basis for early diagnosis and treatment of endometrial polyps in patients with metabolic syndrome. Methods from January 2006 to January 2013, 435 cases of endometrial polyps diagnosed by hysteroscopic pathology were analyzed and divided into benign group (415 cases) and atypical hyperplasia group (20 cases). The clinical data of the two groups were analyzed retrospectively. Results the malignancy rate of endometrial polyps was 4.6%. Univariate analysis showed that the factors associated with atypical hyperplasia or malignant change of endometrial polyps were (BMI), menopausal age, postmenopausal vaginal bleeding, endometrial thickness, waist circumference. Fasting blood glucose, triacylglycerol (TG), serum high density lipoprotein (HDL) (P0.05), multiple regression analysis, BMI, waist circumference, diastolic blood pressure, blood TG, blood HDL, Fasting blood glucose or diagnosed impaired glucose tolerance or diabetes were independent risk factors for endometrial carcinoma with metabolic syndrome (P0.05). Conclusion in menopausal women with endometrial polyps, the malignant change of endometrial polyps is closely related to metabolic syndrome. It is suggested that patients with endometrial polyps with postmenopausal metabolic syndrome should be followed up closely, such as vaginal bleeding. Endometrial thickness 鈮，
本文編號：2391204
[Abstract]:Objective to investigate the relationship between endometrial polyp malignancy and metabolic syndrome after menopause, and to explore its potential malignant change and its risk factors, so as to provide theoretical basis for early diagnosis and treatment of endometrial polyps in patients with metabolic syndrome. Methods from January 2006 to January 2013, 435 cases of endometrial polyps diagnosed by hysteroscopic pathology were analyzed and divided into benign group (415 cases) and atypical hyperplasia group (20 cases). The clinical data of the two groups were analyzed retrospectively. Results the malignancy rate of endometrial polyps was 4.6%. Univariate analysis showed that the factors associated with atypical hyperplasia or malignant change of endometrial polyps were (BMI), menopausal age, postmenopausal vaginal bleeding, endometrial thickness, waist circumference. Fasting blood glucose, triacylglycerol (TG), serum high density lipoprotein (HDL) (P0.05), multiple regression analysis, BMI, waist circumference, diastolic blood pressure, blood TG, blood HDL, Fasting blood glucose or diagnosed impaired glucose tolerance or diabetes were independent risk factors for endometrial carcinoma with metabolic syndrome (P0.05). Conclusion in menopausal women with endometrial polyps, the malignant change of endometrial polyps is closely related to metabolic syndrome. It is suggested that patients with endometrial polyps with postmenopausal metabolic syndrome should be followed up closely, such as vaginal bleeding. Endometrial thickness 鈮，
本文編號：2391204
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