【摘要】：目的：調(diào)查分析新疆部分地區(qū)子宮內(nèi)膜異位癥發(fā)病的一般流行病學(xué)特點(diǎn),并探討子宮內(nèi)膜異位癥發(fā)病的相關(guān)因素。方法：采用病例對(duì)照研究。病例組選取2011年12月至2013年9月于蘭州軍區(qū)烏魯木齊總醫(yī)院經(jīng)手術(shù)病理證實(shí)為子宮內(nèi)膜異位癥的患者146例(包含1例伴陰道閉鎖的青春期子宮內(nèi)膜異位癥)。對(duì)照組為同期門診體檢正常的婦女206例。首先對(duì)146例病例組患者資料進(jìn)行單獨(dú)分析；再除外病例組1例特殊病例資料后,對(duì)兩組的月經(jīng)初潮年齡、月經(jīng)量、月經(jīng)周期、經(jīng)期、痛經(jīng)、生育史、哺乳史、輸卵管通液史或是輸卵管造影史、吸煙史、避孕措施等方面進(jìn)行單因素和多因素非條件Logistic回歸模型分析,篩選出子宮內(nèi)膜異位癥發(fā)病相關(guān)因素。結(jié)果：經(jīng)非條件單因素Logistic回歸分析結(jié)果顯示：月經(jīng)初潮年齡、月經(jīng)周期、輸卵管通液或造影術(shù)、剖宮產(chǎn)次、避孕方法以及主動(dòng)吸煙對(duì)子宮內(nèi)膜異位癥的發(fā)病無顯著影響(P0.05),經(jīng)量、經(jīng)期、哺乳、孕次、不孕、人工流產(chǎn)或?qū)m腔操作史與子宮內(nèi)膜異位癥的發(fā)病有顯著相關(guān)性(P0.05)；控制混雜因素后,經(jīng)多因素Logistic回歸模型分析,結(jié)果顯示：經(jīng)期長(zhǎng)(6天)、痛經(jīng)、3次及以上人工流產(chǎn)術(shù)或?qū)m腔操作史是子宮內(nèi)膜異位癥發(fā)病的危險(xiǎn)因素(偏回顧系數(shù)β依次為2.007、1.779、2.050,OR值依次為7.981、5.921、7.769),P0.05,具有統(tǒng)計(jì)學(xué)意義；而經(jīng)量少(20m1)、生產(chǎn)因素是子宮內(nèi)膜異位癥發(fā)病的保護(hù)因素(偏回歸系數(shù)β依次為-1.322、-1.776、-2.387、-3.268,OR值依次為0.267、0.169、0.092、0.038),P0.05,具有統(tǒng)計(jì)學(xué)意義。結(jié)論：子宮內(nèi)膜異位癥發(fā)病的相關(guān)因素有經(jīng)期長(zhǎng)(6天)、經(jīng)量少(20m1)、生產(chǎn)次數(shù)、痛經(jīng)、3次及以上人工流產(chǎn)術(shù)或?qū)m腔操作史；危險(xiǎn)因素是經(jīng)期6天、痛經(jīng)、3次及以上人工流產(chǎn)或?qū)m腔操作史：保護(hù)因素是經(jīng)量20m1、生產(chǎn)次數(shù)多；因此縮短經(jīng)期、緩解痛經(jīng)、做好計(jì)劃生育、減少人工流產(chǎn)術(shù)或?qū)m腔操作次數(shù)有望減少或是預(yù)防子宮內(nèi)膜異位癥的發(fā)病。
[Abstract]:Objective: to investigate and analyze the general epidemiological characteristics of endometriosis in some areas of Xinjiang, and to explore the related factors of endometriosis. Methods: a case-control study was conducted. From December 2011 to September 2013, 146 patients with endometriosis (including 1 adolescent endometriosis with vaginal atresia) were selected from Urumqi General Hospital of Lanzhou military region. The control group was 206 women with normal physical examination in the same period. The data of 146 cases were analyzed separately. After one special case in the case group was excluded, the menarche age, menstrual volume, menstrual cycle, dysmenorrhea, birth history, lactation history, salpingography history, smoking history of the two groups were recorded. Univariate and multivariate non-conditional Logistic regression models were used to screen the related factors of endometriosis. Results: the unconditioned univariate Logistic regression analysis showed that: menarche age, menstrual cycle, fallopian tube effusion or contrast, cesarean section, Contraceptive methods and active smoking had no significant effect on the incidence of endometriosis (P0.05). The history of induced abortion or uterine cavity operation was significantly correlated with the incidence of endometriosis (P0.05). After controlling for confounding factors, multivariate Logistic regression model analysis showed that menstrual period was long (6 days), dysmenorrhea, dysmenorrhea, Three or more times of induced abortion or history of uterine cavity operation were the risk factors of endometriosis (partial retrospective coefficient 尾 was 2.007 / 1.779 / 2.050) (OR = 7.981 / 5.921 / 7.769), with statistical significance (P < 0.05). However, the factor of production was the protective factor of endometriosis (the partial regression coefficient 尾 was -1.322- 1.776- 2.387U -3.268m), and the OR was 0.267U 0.169U 0.092n 0.038, P 0.05, P < 0.05, P < 0.01). It has statistical significance. Conclusion: the related factors of endometriosis include long menstrual period (6 days), low menstrual volume (20m1), number of labor, dysmenorrhea, 3 or more induced abortion or history of uterine cavity operation. The risk factors were menstrual period 6 days dysmenorrhea 3 or more induced abortion or uterine cavity operation history. Therefore, shortening menstrual period, relieving dysmenorrhea, doing family planning well, reducing the number of induced abortion or uterine cavity operation are expected to reduce or prevent the incidence of endometriosis.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R711.71

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 周應(yīng)芳;子宮內(nèi)膜異位癥發(fā)病的家族傾向[J];北京醫(yī)學(xué);1994年02期

2 李海燕,劉芳,史繼芳,梁占光;輸卵管通液術(shù)與子宮內(nèi)膜異位癥的關(guān)系[J];大理醫(yī)學(xué)院學(xué)報(bào);2001年04期

3 王紅靜,吳艷喬,陳新蓮,郭妍南,宋雪凌,田超,王俊英;成都市女性子宮內(nèi)膜異位癥危險(xiǎn)因素的探討[J];四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2003年04期

4 林琳;王平;;腹壁切口子宮內(nèi)膜異位癥112例臨床分析[J];四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2009年03期

5 賴曉嵐;華興;陳燕輝;;子宮內(nèi)膜異位癥在位內(nèi)膜中神經(jīng)纖維的表達(dá)[J];山東大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2011年01期

6 于玲;田永杰;;子宮內(nèi)膜異位癥發(fā)病相關(guān)因素的臨床研究[J];山東大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2013年02期

7 張慶霞;冷金花;郎景和;劉珠鳳;孫大為;朱蘭;;青少年子宮內(nèi)膜異位癥29例臨床分析[J];現(xiàn)代婦產(chǎn)科進(jìn)展;2007年12期

8 張?zhí)N玉,黃惠芳,連利娟,黃榮麗,郎景和;子宮內(nèi)膜異位癥與卵巢上皮性癌的關(guān)系[J];中華婦產(chǎn)科雜志;1999年09期

9 楊佳欣,沈鏗,冷金花,郎景和;青少年子宮內(nèi)膜異位癥六例臨床分析[J];中華婦產(chǎn)科雜志;2001年12期

10 郎景和;;子宮內(nèi)膜異位癥研究的任務(wù)與展望(之二)[J];中華婦產(chǎn)科雜志;2006年10期

，

本文編號(hào)：2356213