米非司酮聯(lián)合血府逐瘀膠囊治療子宮肌瘤的臨床效果及安全性
[Abstract]:Objective: to investigate the clinical effect and safety of mifepristone combined with Xuefu Zhuyu capsule in the treatment of uterine leiomyoma. Methods: from June 2012 to June 2014, 60 patients with uterine leiomyoma were randomly divided into observation group and control group. In the observation group, 30 cases were treated with mifepristone combined with Xuefu Zhuyu capsule. The control group (30 cases) was treated with mifepristone. The volume of uterus, volume of uterine leiomyoma, hormone content (LH,FSH,P,E2), therapeutic effect and adverse reactions (nausea, headache, fatigue) were compared between the two groups. Results: after treatment, there was a significant difference in the volume of uterus between the observation group and the control group, which was smaller than that in the control group (t 9.3029 Pu 0.0003). The volume of uterine leiomyoma in the observation group was smaller than that in the control group, and there was statistical difference between the two groups (t = 3.8804, P 0.0001). The content of LH,FSH,P,E2 in the observation group was lower than that in the control group (P0.05), the therapeutic effect of the observation group was better than that of the control group, and there was statistical difference between the two groups. The incidence of postoperative headache in the observation group and the control group was 0.00% and 13.33 respectively, and there was a significant difference between the two groups (蠂 ~ 2 / 4.2857 / P ~ (0.0384). The overall incidence rates of adverse reactions in the observation group and the control group were 6.67% and 36.67%, respectively. There was a significant difference between the two groups (蠂 ~ 2 = 7.9542, P < 0.0048). Conclusion: mifepristone combined with Xuefu Zhuyu capsule in the treatment of uterine leiomyoma has good clinical efficacy, high safety and good prognosis.
【作者單位】: 義烏市中心醫(yī)院婦產(chǎn)科;
【分類號】:R737.33
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