本文選題：HBV　切入點(diǎn)：孕產(chǎn)婦　出處：《中國(guó)婦產(chǎn)科臨床雜志》2015年03期

【摘要】：目的研究孕婦攜帶乙型肝炎病毒(HBV)對(duì)母嬰結(jié)局的影響。方法選取2011年1月至2013年12月在南方醫(yī)科大學(xué)中山市博愛(ài)醫(yī)院產(chǎn)檢及分娩的乙肝表面抗原(HBsAg)陽(yáng)性的孕產(chǎn)婦124例為研究組,選取同期產(chǎn)檢及分娩的乙肝表面抗原(HBsAg)陰性的健康孕產(chǎn)婦124例為對(duì)照組,比較兩組不良妊娠結(jié)局的發(fā)生率。結(jié)果 1研究組中孕產(chǎn)婦發(fā)生妊娠期高血壓疾病、妊娠期糖尿病、妊娠期肝內(nèi)膽汁淤積癥、肝功能損害及產(chǎn)后出血的概率均明顯高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P均0.05);2研究組中發(fā)生胎兒窘迫、新生兒小于胎齡兒、新生兒肺炎、新生兒高膽紅素血癥的概率均明顯高于對(duì)照組,差異均有統(tǒng)計(jì)學(xué)意義(P均0.05);3研究組中單陽(yáng)組的母兒并發(fā)癥與對(duì)照組比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P均0.05);4研究組中雙陽(yáng)組母兒并發(fā)癥明顯高于單陽(yáng)組,差異均有統(tǒng)計(jì)學(xué)意義(P均0.05)。結(jié)論孕期攜帶HBV可明顯增加孕婦妊娠期及分娩期并發(fā)癥的發(fā)生率,同時(shí)增加胎兒窘迫、新生兒肺炎及新生兒高膽紅素血癥的發(fā)生率,對(duì)母嬰影響較大,臨床上要引起重視。
[Abstract]:Objective to study the effect of hepatitis B virus (HBV) on maternal and infant outcomes in pregnant women.Methods from January 2011 to December 2013, 124 pregnant women who were positive for HBsAg in birth and delivery in Boai Hospital, Zhongshan City, Southern Medical University, were selected as the study group.124 healthy pregnant women with HBsAg negative in the same period of labor and delivery were selected as control group. The incidence of adverse pregnancy outcome was compared between the two groups.Results 1the probability of hypertensive disorder complicating pregnancy, gestational diabetes mellitus, intrahepatic cholestasis of pregnancy, liver function damage and postpartum hemorrhage in the study group were significantly higher than those in the control group.The difference was statistically significant (P < 0.05). The probability of fetal distress, neonatal pneumonia and neonatal hyperbilirubinemia in the study group was significantly higher than that in the control group, and the incidence of neonatal fetal distress, neonatal pneumonia and neonatal hyperbilirubinemia were significantly higher than those in the control group.There was no significant difference in maternal and fetal complications between single positive group and control group (P 0.05). The maternal and infant complications in double positive group were significantly higher than those in single positive group, and the difference was statistically significant (P 0.05).Conclusion carrying HBV during pregnancy can significantly increase the incidence of complications during pregnancy and delivery, and increase the incidence of fetal distress, neonatal pneumonia and neonatal hyperbilirubinemia.
【作者單位】： 南方醫(yī)科大學(xué)中山市博愛(ài)醫(yī)院婦產(chǎn)科;
【分類(lèi)號(hào)】：R714.251

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本文編號(hào)：1728880