本文選題：解脲脲原體　切入點：沙眼衣原體　出處：《青島大學(xué)》2014年碩士論文

【摘要】：目的檢測威海地區(qū)女性不孕癥患者解脲脲原體(ureaplasma urealyticum, UU)和沙眼衣原體(chlamydia trachomatis, CT)的感染狀況,以探討UU、CT感染與女性不孕的相關(guān)性。 方法選取2013年1月到12月在威海市婦幼保健院生殖醫(yī)學(xué)門診就診的女性不孕癥患者731例為不孕組,同期在體檢中心查體的已生育健康女性200例做為對照組,采集宮頸分泌物標(biāo)本,應(yīng)用實時熒光定量PCR(TaqMan PCR)行UU-DNA、CT-DNA定量檢測。 結(jié)果(1)不孕癥病因分析：731位不孕癥患者中以輸卵管性不孕最多,占49.7%,排卵異常、子宮內(nèi)膜異位癥、免疫性不孕患者及其他病因患者分別占32.4%、5.6%、8.2%和4.1%。(2)不孕組UU、CT及UU+CT的感染率分別為53.9%(394/731)、29.8%(218/731)和12.6%(92/731),對照組為24%(48/200)、17.5%(35/200)和5%(10/200),均有顯著性差異(P0.001)。(3)年齡分布：731例患者中26-30歲年齡組的UU、CT、UU+CT的感染率最高分別占25.2%、15.3%、7.3%；31-35歲年齡組次之,分別占16.8%、12.2%、4.4%；20-25歲年齡組分別占3.4%、0.8%、0.4%；36-40歲年齡組分別占6.3%、1.1%、0.4%；41-45歲年齡組分別占2.2%、0.4%、0.1%。結(jié)論威海地區(qū)女性不孕患者UU、CT、UU+CT陽性率明顯高于正常女性,表明UU、CT感染與女性不孕有一定的相關(guān)性；UU、CT檢測應(yīng)成為不孕癥的常規(guī)實驗室檢查項目。
[Abstract]:Objective to detect the infection of Ureaplasma Urealyticum (UUU) and chlamydia trachomatis( CTT) in female infertility patients in Weihai area, and to explore the correlation between UUCT infection and female infertility.Methods from January to December 2013, 731 female infertility patients were selected as infertile group and 200 healthy women who had been examined in the physical examination center were selected as the control group in the reproductive medicine outpatient clinic of Weihai Maternal and Child Health Hospital from January to December 2013.The samples of cervical secretions were collected and the UU-DNA CT-DNA quantitative detection was performed by real-time fluorescence quantitative PCR(TaqMan.Results 1) Analysis of the etiology of infertility; among the 731 infertility patients, oviduct infertility was the most common, accounting for 49.7%, ovulation abnormality, endometriosis,鍏嶇柅鎬т笉瀛曟?zhèn)ｈ�呭強鍏朵粬鐥呭洜鎮(zhèn)ｈ，

本文編號：1705246