本文選題：先兆流產(chǎn)　切入點：影響因素　出處：《安徽醫(yī)科大學(xué)學(xué)報》2015年11期

【摘要】：目的分析試管嬰兒的孕婦發(fā)生先兆流產(chǎn)的相關(guān)影響因素,為預(yù)防試管嬰兒孕婦發(fā)生先兆流產(chǎn)提供科學(xué)依據(jù)。方法病例組選取因患先兆流產(chǎn)而住院的孕婦87例;對照組均來自于同期做試管嬰兒且無先兆流產(chǎn)的孕婦,共92例,調(diào)查試管嬰兒孕婦先兆流產(chǎn)的影響因素。應(yīng)用Epi Data3.1數(shù)據(jù)庫及SPSS 17.0軟件進行數(shù)據(jù)錄入及統(tǒng)計分析,分析方法主要包括秩和檢驗、χ2檢驗、單因素和多因素條件Logistic回歸分析;并計算各影響因素與先兆流產(chǎn)的關(guān)聯(lián)強度(OR值)及其95%CI。結(jié)果單因素分析結(jié)果表明:兩組研究對象的職業(yè)、文化程度、身高、體重、體質(zhì)指數(shù)差異無統(tǒng)計學(xué)意義(P0.05)。但年齡差異有統(tǒng)計學(xué)意義(P0.05),兩組研究對象在不良妊娠史、既往疾病史、不孕類型、不孕年限方面差異無統(tǒng)計學(xué)意義(P0.05);而兩組在移植時子宮內(nèi)膜厚度、移植的胚胎數(shù)目、移植胚胎的周期類型、孕婦的焦慮評分顯示有統(tǒng)計學(xué)意義。多因素條件Logistic回歸分析結(jié)果顯示,胚胎移植時子宮內(nèi)膜的厚度、移植胚胎的周期類型、妊娠期心理壓力是先兆流產(chǎn)發(fā)生的獨立危險因素(OR=1.169、0.304、0.898,95%CI分別為1.005~1.361、0.135~0.683、0854~0.944)。結(jié)論移植時子宮內(nèi)膜厚度、移植胚胎的周期類型、妊娠期心理壓力可能是先兆流產(chǎn)發(fā)生的獨立危險因素。
[Abstract]:Objective to analyze the influencing factors of threatened abortion in IVF pregnant women, and to provide scientific basis for prevention of threatened abortion. Methods 87 pregnant women hospitalized with threatened abortion were selected in the case group. The control group were all from 92 pregnant women who had no threatened abortion in the same period. The influencing factors of threatened abortion were investigated. The data input and statistical analysis were carried out by using Epi Data3.1 database and SPSS 17.0 software. The main methods of analysis included rank sum test, 蠂 2 test, univariate and multivariate conditional Logistic regression analysis, and calculated the relative strength OR value of each influencing factor and threatened abortion) and 95 CIs. Results the results of univariate analysis showed the occupation of the two groups of subjects. There was no significant difference in education level, height, weight, body mass index (BMI). But there was significant difference in age (P 0.05). The subjects of the two groups were in the history of bad pregnancy, the history of previous disease, the type of infertility. There was no significant difference in the length of infertility between the two groups (P 0.05), but the thickness of endometrium, the number of embryos transferred, and the period of embryo transfer were different between the two groups. The anxiety scores of pregnant women were statistically significant. Multivariate conditional Logistic regression analysis showed that the thickness of endometrium at the time of embryo transfer, the type of cycle of embryo transfer, Psychological stress during pregnancy was the independent risk factor of threatened abortion. The CI was 1.005U 1.361U 0.135U 0.683n08540.9440.Conclusion the thickness of endometrium, the period of embryo transfer and the psychological stress during pregnancy may be the independent risk factors for the occurrence of threatened abortion.
【作者單位】： 安徽醫(yī)科大學(xué)第一附屬醫(yī)院生殖醫(yī)學(xué)中心;安徽醫(yī)科大學(xué)公共衛(wèi)生學(xué)院;
【基金】：國家重大科學(xué)研究計劃(編號:2012CB944704)
【分類號】：R714.21

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