本文選題：重度子癇前期　切入點：未足月　出處：《實用婦產(chǎn)科雜志》2015年12期

【摘要】：目的:探討24小時尿蛋白定量和血清白蛋白水平與未足月重度子癇前期(SPE)母兒結(jié)局的關(guān)系。方法:選擇2009年7月至2013年12月于本院產(chǎn)科住院治療并分娩的孕周37周的99例重度子癇前期的孕婦及其分娩的新生兒作為研究對象�；仡櫺苑治鲈袐D24小時尿蛋白定量、血清白蛋白結(jié)果及主要母兒并發(fā)癥和新生兒預(yù)后。結(jié)果:124小時尿蛋白定量≥5 g/24 h組胎兒生長受限(FGR)和腦癱的發(fā)生率明顯高于5 g/24 h組,新生兒體重(1765.0±567.4 g)也明顯輕于后者(2000.7±607.4 g)(P0.05);兩組比較HELLP綜合征、子癇、胎盤早剝、腎功能損害、心功能損害、視網(wǎng)膜脫落、胎兒窘迫、胎死宮內(nèi)(IUFD)引產(chǎn)的發(fā)生率,及新生兒死亡、機械通氣使用率、肺泡表面活性物質(zhì)(PS)使用率、窒息、新生兒呼吸窘迫綜合征(NRDS)、顱內(nèi)出血、敗血癥、新生兒缺血缺氧性腦病(HIE)的發(fā)生率差異均無統(tǒng)計學(xué)意義(P0.05)。2血清白蛋白25 g/L組活產(chǎn)兒機械通氣的使用率、窒息率和NRDS發(fā)生率均明顯高于血清白蛋白≥25 g/L組,且前者新生兒的體重(1803.2±559.3 g)明顯輕于后者(2115.2±639.5 g)(P0.05);兩組其余指標(biāo)比較差異均無統(tǒng)計學(xué)意義(P0.05)。3早發(fā)型重度子癇前期與晚發(fā)型重度子癇前期組比較,前者血清白蛋白25 g/L、新生兒體重1500 g的發(fā)生率均明顯高于后者(P0.01),兩組患者24小時尿蛋白定量≥5 g/24 h的發(fā)生率比較,差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論:24小時尿蛋白定量與血清白蛋白水平在某種程度上可以反映未足月重度子癇前期新生兒的預(yù)后,可作為其評價指標(biāo),且血清白蛋白結(jié)果更優(yōu)于24小時尿蛋白定量。
[Abstract]:Objective: to investigate the relationship between 24 hour urinary protein quantification and serum albumin level and the maternal and fetal outcome of severe preeclampsia.Methods: from July 2009 to December 2013, 99 pregnant women with severe preeclampsia and their newborns who were hospitalized and delivered in our hospital during 37 weeks of gestation were selected as the study objects.The 24-hour urinary protein quantification, serum albumin, main maternal and fetal complications and neonatal prognosis were analyzed retrospectively.Results the incidence of fetal growth restriction (FG) and cerebral palsy (FG) and cerebral palsy were significantly higher in the 124-hour urine protein ration 鈮，

本文編號：1698464