發(fā)布時(shí)間：2018-03-22 09:46

  本文選題：子癇前期　切入點(diǎn)：復(fù)發(fā)　出處：《中國(guó)婦產(chǎn)科臨床雜志》2015年05期 　論文類型：期刊論文

【摘要】：目的探討子癇前期復(fù)發(fā)對(duì)妊娠結(jié)局的影響。方法回顧分析2009年1月至2014年3月在北京大學(xué)第三醫(yī)院住院并分娩的有過(guò)子癇前期病史的臨床觀察病例資料82例,按照此次妊娠有無(wú)子癇前期復(fù)發(fā)分為復(fù)發(fā)子癇前期組(RPE組)37例和未復(fù)發(fā)子癇前期組45例(NRPE組),與同期無(wú)子癇前期病史此次妊娠初發(fā)子癇前期的病例90例(PPE組)進(jìn)行比較,分析臨床結(jié)局差異。結(jié)果 RPE組合并內(nèi)科疾病者比例、合并慢性高血壓者比例均明顯高于NRPE組及PPE組(P0.001、0.001);RPE組子癇前期診斷孕周和妊娠分娩孕周均明顯早于PPE組(P=0.009、0.037);RPE組輕度子癇前期者所占比例明顯低于PPE組,早發(fā)型子癇前期者所占比例、慢性高血壓合并子癇前期者所占比例均明顯高于PPE組(P=0.015、0.004、0.001);RPE組新生兒出生體重明顯低于PPE組,小于孕齡兒比例、活產(chǎn)兒入住新生兒重癥監(jiān)護(hù)病房比例明顯高于PPE組(P=0.048、0.034、0.015)。結(jié)論復(fù)發(fā)子癇前期較初發(fā)子癇前期有更嚴(yán)重的臨床結(jié)局,母體存在更多的潛在病理狀況。應(yīng)注重復(fù)發(fā)子癇前期的防范,最大限度減少疾病復(fù)發(fā),改善臨床結(jié)局。
[Abstract]:Objective to investigate the effect of preeclampsia recurrence on pregnancy outcome. Methods 82 cases with history of pre-eclampsia who were hospitalized and delivered in the third Hospital of Peking University from January 2009 to March 2014 were retrospectively analyzed. According to whether preeclampsia recurred in this pregnancy, there were 37 cases of recurrent preeclampsia in RPE group and 45 cases in non-recurrent preeclampsia group, compared with 90 cases of preeclampsia with no history of preeclampsia in the same period. Results the proportion of patients with RPE combined with internal medical diseases was analyzed. The proportion of patients with chronic hypertension was significantly higher than that of NRPE group and PPE group. The proportion of mild preeclampsia in PPE group was significantly earlier than that in PPE group, and the proportion of early onset preeclampsia group was significantly lower than that in PPE group. The proportion of patients with chronic hypertension complicated with preeclampsia was significantly higher than that of PPE group (P 0.015 0. 004). The birth weight of newborns in PPE group was significantly lower than that in PPE group, and the proportion of pregnant infants was lower than that in PPE group. The proportion of live infants admitted to neonatal intensive care unit was significantly higher than that of PPE group. Conclusion recurrent preeclampsia has more severe clinical outcome than that of primary preeclampsia, and there are more potential pathological conditions in mother body, and attention should be paid to the prevention of recurrent preeclampsia. Minimize the recurrence of disease and improve the clinical outcome.
【作者單位】： 北京大學(xué)第三醫(yī)院婦產(chǎn)科;
【基金】：國(guó)家自然科學(xué)基金(81370723) 北京市自然科學(xué)基金(7132215)
【分類號(hào)】：R714.244

【共引文獻(xiàn)】

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5 沙同葉;徐琳;;子癇前期與遺傳易感基因多態(tài)性的研究進(jìn)展[J];中國(guó)婦產(chǎn)科臨床雜志;2015年04期

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本文編號(hào)：1648112