發(fā)布時(shí)間：2018-03-01 14:16

  本文關(guān)鍵詞： 軟組織腫瘤 富于細(xì)胞性血管纖維瘤 病理診斷　出處：《臨床與實(shí)驗(yàn)病理學(xué)雜志》2017年03期 　論文類型：期刊論文

【摘要】：目的 探討富于細(xì)胞性血管纖維瘤(cellular angiofibroma,CAF)的臨床病理、免疫表型、鑒別診斷及預(yù)后。方法對(duì)3例CAF行HE和免疫組化Max Vision法染色,分析臨床資料并復(fù)習(xí)相關(guān)文獻(xiàn)。結(jié)果 CAF瘤細(xì)胞豐富,呈短梭形,核卵圓形,偶見核分裂象;瘤組織中含大量管壁厚薄不一的血管,部分管壁玻璃樣變性,間質(zhì)可見水腫及黏液樣變性。免疫表型:瘤細(xì)胞vimentin呈彌漫陽性,CD34、ER、PR呈陽性或部分陽性,SMA、desmin、S-100均呈陰性。結(jié)論 CAF是一種少見的間葉性腫瘤,多發(fā)于兩性生殖區(qū),其鏡下以密集的短梭形細(xì)胞和豐富血管為特征,治療以手術(shù)切除為主,患者預(yù)后良好。
[Abstract]:Objective to investigate the clinicopathology, immunophenotype, differential diagnosis and prognosis of cellular angiofibroma (CAF). Methods three cases of CAF were examined by HE and immunohistochemical Max Vision staining. Results there were plenty of CAF tumor cells with short fusiform shape, oval nucleus and occasional mitosis. There were a large number of vessels with different thickness and thickness in the tumor tissue, some of them were hyaluronic degeneration. Edema and myxoid degeneration were observed in stroma. Immunophenotype: vimentin was diffuse positive and CD34ERP was positive or SMA desminminator S-100 was negative. Conclusion CAF is a rare mesenchymal tumor, which is mainly located in the bilateral reproductive region. It is characterized by dense fusiform cells and abundant blood vessels under microscope. Surgical resection is the main treatment, and the prognosis of the patients is good.
【作者單位】： 河南省人民醫(yī)院病理科;
【分類號(hào)】：R737.3

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1 雪亮;岳樹源;;鼻竇內(nèi)血管纖維瘤手術(shù)治療[A];2011中華醫(yī)學(xué)會(huì)神經(jīng)外科學(xué)學(xué)術(shù)會(huì)議論文匯編[C];2011年

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