本文關(guān)鍵詞：宮頸絨毛管狀腺癌38例臨床病理分析　出處：《現(xiàn)代婦產(chǎn)科進(jìn)展》2015年10期 　論文類型：期刊論文

  更多相關(guān)文章： 絨毛管狀腺癌 宮頸 臨床病理特點

【摘要】：目的:探討宮頸絨毛管狀腺癌(VGA)的臨床病理特點及預(yù)后影響因素。方法:收集北京協(xié)和醫(yī)院婦產(chǎn)科于1995年1月至2015年1月收治的503例宮頸腺癌的病例資料,其中VGA 38例,分析患者的年齡分布、臨床病理特點、預(yù)后及其影響因素。結(jié)果:VGA患者中位年齡為41.0歲(27~76歲)。最常見的臨床癥狀為接觸性出血(68.5%);IA期3例,IB期31例,IIA期2例,IIB期2例;34例患者接受根治性子宮切除術(shù)及(或)盆腔淋巴結(jié)清掃術(shù),其中1例患者發(fā)現(xiàn)淋巴血管間隙受累,1例卵巢轉(zhuǎn)移,1例復(fù)發(fā);2例患者放化療后行全子宮切除術(shù);2例患者行保留生育功能的手術(shù)。38例VGA與同期收治的326例宮頸腺癌的臨床病理特點進(jìn)行比較,發(fā)現(xiàn)兩組的腫瘤分化程度、宮頸肌層浸潤深度、淋巴脈管間隙浸潤、淋巴結(jié)轉(zhuǎn)移、腫瘤復(fù)發(fā)等因素有統(tǒng)計學(xué)差異(P0.05)。結(jié)論:VGA的發(fā)病年齡較輕,以外生型腫瘤多見,診斷時絕大多數(shù)患者處于臨床早期,腫瘤分化程度較好,浸潤深度較淺,淋巴脈管間隙浸潤及淋巴結(jié)轉(zhuǎn)移少見,是預(yù)后較好的宮頸腺癌型別,行保留生育功能的手術(shù)治療是可行的。
[Abstract]:Objective: to study the VGA of cervical villous tubular adenocarcinoma. Methods: data of 503 cases of cervical adenocarcinoma admitted from January 1995 to January 2015 were collected. The age distribution and clinicopathological characteristics of 38 patients with VGA were analyzed. Results the median age of the patients with VGA was 41.0 years old and 2776 years old. The most common clinical symptom was contact hemorrhage. There were 3 cases of stage IA, 31 cases of stage IIA and 2 cases of stage IIB. 34 patients underwent radical hysterectomy and / or pelvic lymph node dissection. Total hysterectomy was performed in 2 patients after radiotherapy and chemotherapy. The clinicopathological features of 2 cases of VGA and 326 cases of cervical adenocarcinoma were compared. The degree of tumor differentiation and the depth of myometrium infiltration were found in the two groups. There were significant differences in lymphatic vascular space invasion, lymph node metastasis and tumor recurrence (P 0.05). Conclusion the age of VGA is younger and ectogenic tumors are more common. Most of the patients were in the early clinical stage, the tumor differentiation was better, the depth of invasion was shallow, the lymphatic vascular space infiltration and lymph node metastasis were rare, and the prognosis of cervical adenocarcinoma was better. It is feasible to perform surgical treatment to preserve fertility function.
【作者單位】： 中國醫(yī)學(xué)科學(xué)院北京協(xié)和醫(yī)院婦產(chǎn)科;
【基金】：國家自然科學(xué)基金(No:H1621)
【分類號】：R737.33
【正文快照】： Clinical and pathological analysis of patients with villoglandular adenocarcinoma of thecervix:a retrospective study of 38 cases.Liu Pengfei,Guo Peng,Wu Ming,et al.Departmentof Obstetrics and Gynecology,Peking Union Medical College Hospital,Chinese Acade

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相關(guān)期刊論文 前1條

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【共引文獻(xiàn)】

相關(guān)期刊論文 前10條

1 朱孝嚴(yán);張煒e，

本文編號：1418506