本文關(guān)鍵詞：動(dòng)態(tài)血糖在妊娠期糖尿病患者胰島素強(qiáng)化治療期間的臨床應(yīng)用價(jià)值　出處：《重慶醫(yī)學(xué)》2015年36期 　論文類型：期刊論文

  更多相關(guān)文章： 糖尿病 妊娠 動(dòng)態(tài)血糖監(jiān)測(cè) 胰島素 母兒預(yù)后

【摘要】：目的探討連續(xù)動(dòng)態(tài)血糖監(jiān)測(cè)(CGMS)在妊娠期糖尿病(GDM)患者胰島素強(qiáng)化治療期間的臨床應(yīng)用價(jià)值。方法隨機(jī)選取2013年3月至2014年2月本院門(mén)診妊娠期糖尿病篩查確診的GDM患者65例,均采取胰島素泵持續(xù)皮下輸注胰島素(CSII)治療,隨機(jī)分為CGMS組(n=34)和指血監(jiān)測(cè)組(n=31)。結(jié)果兩組患者血糖均于餐前明顯降低,餐后明顯升高,波動(dòng)幅度均較大,并均于睡前至早餐前血糖趨于穩(wěn)定,波動(dòng)幅度較小。兩組患者均達(dá)相同強(qiáng)化血糖目標(biāo)值,CGMS組患者治療期血糖平均值明顯低于指血監(jiān)測(cè)組(P0.05);CGMS組患者血糖達(dá)標(biāo)時(shí)間明顯短于指血監(jiān)測(cè)組(P0.05);兩組患者治療期間胰島素劑量比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);CGMS組患者治療期間低血糖發(fā)生次數(shù)明顯低于指血監(jiān)測(cè)組(P0.05);CGMS組患者新生兒低血糖、高膽紅素血癥的發(fā)生率明顯低于指血監(jiān)測(cè)組(P0.05)。結(jié)論應(yīng)用CGMS監(jiān)測(cè)GDM患者血糖變化,有利于臨床醫(yī)師針對(duì)患者血糖動(dòng)態(tài)變化趨勢(shì)制訂個(gè)體化用藥方案,進(jìn)而有效改善患者母兒預(yù)后。
[Abstract]:Objective to investigate the effect of continuous glucose monitoring (CGMS) in gestational diabetes mellitus (GDM) during intensive therapy, the clinical application value of insulin. 65 GDM patients were randomly selected from March 2013 to February 2014 in the outpatient screening of diabetes mellitus during pregnancy diagnosed cases, adopt continuous subcutaneous insulin infusion (CSII) therapy, were randomly divided into CGMS group (n=34) and the blood monitoring group (n=31). The results of two groups of patients with blood glucose levels were significantly lower in before meals, after meals increased significantly, fluctuations are large, and before going to bed before breakfast to blood sugar stable, wave amplitude is smaller. Two groups of patients were the same as intensive blood glucose target, CGMS group treatment of patients with blood glucose was significantly lower than the average value of finger blood monitoring group (P0.05); group CGMS blood glucose time was shorter than the finger blood monitoring group (P0.05); the two groups of patients during treatment with insulin dose was no significant difference (P0. 05); group CGMS patients during the treatment of hypoglycemia was significantly lower than that of monitoring blood group (P0.05); CGMS group of patients with neonatal hypoglycemia, hyperbilirubinemia incidence was significantly lower than that of monitoring blood group (P0.05). Conclusion the changes of blood glucose of patients monitored by CGMS GDM, and help clinicians individualized treatment programs for patients with dynamic changes in blood glucose trends then, effectively improve the patient's prognosis.

【作者單位】： 江蘇省南京市第一醫(yī)院內(nèi)分泌科;
【分類號(hào)】：R714.256
【正文快照】： 病率呈逐年上升趨勢(shì),占妊娠期糖代謝紊亂的90%[1]。GDM可使母體并發(fā)高血壓、羊水過(guò)多、糖尿病眼病等嚴(yán)重并發(fā)癥,同時(shí)還可能導(dǎo)致胎兒生長(zhǎng)受限、發(fā)育異常、甚至死亡等,嚴(yán)重影響孕婦的產(chǎn)后健康和新生兒預(yù)后[2]。血糖監(jiān)測(cè)是診斷GDM、制訂個(gè)體化血糖控制方案、監(jiān)護(hù)母體和胎兒安危的

【參考文獻(xiàn)】

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