本文關(guān)鍵詞：間苯三酚與硫酸鎂治療晚期先兆流產(chǎn)的Meta分析　出處：《中華臨床醫(yī)師雜志(電子版)》2016年21期 　論文類型：期刊論文

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【摘要】：目的系統(tǒng)分析比較間苯三酚及硫酸鎂在晚期先兆流產(chǎn)中的療效。方法檢索中國生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫、萬方、知網(wǎng)、維普、百度等國內(nèi)中文數(shù)據(jù)庫收錄的公開發(fā)表與研究目的相關(guān)的隨機(jī)對(duì)照研究文獻(xiàn),應(yīng)用Rev Man 5.3軟件對(duì)滿足條件的數(shù)據(jù)進(jìn)行合并分析,對(duì)兩組藥物治療起效時(shí)間、宮縮緩解時(shí)間、保胎的有效率以及不同方法的不良反應(yīng)發(fā)生率進(jìn)行分析比較。結(jié)果 6個(gè)隨機(jī)對(duì)照試驗(yàn)納入研究分析。間苯三酚與硫酸鎂組相比,治療起效時(shí)間晚0.75 h,95%可信區(qū)間為0.25~1.24,兩組宮縮緩解時(shí)間無統(tǒng)計(jì)學(xué)差異(P=0.5),硫酸鎂相比,間苯三酚治療先兆流產(chǎn)有效率的RR值為1.09(95%可信區(qū)間為1.03~1.16),不良反應(yīng)的RR值為0.02(95%可信區(qū)間為0.01~0.05)。結(jié)論間苯三酚治療先兆流產(chǎn)的療效優(yōu)于硫酸鎂,且不良反應(yīng)發(fā)生率明顯降低。
[Abstract]:Effect of system analysis comparison between benzene three phenol and Magnesium Sulfate in the late threatened abortion. Methods to retrieve the China biomedical literature database, Wanfang, CNKI, VIP, indexed by Baidu and other domestic Chinese database published the randomized controlled study and research related to the purpose of offering, using Rev Man 5.3 software combined with analysis of the data which meet the conditions on two groups of drug treatment, onset time, uterine remission time, tocolysis occurred efficiency and adverse reactions of different methods are analyzed and compared. Results the rate of 6 randomized controlled trials were included in the study. The analysis of benzene three phenol compared with the Magnesium Sulfate group, the onset time of the treatment at 0.75 h, 95% confidence interval 0.25~1.24, two the remission time of group contractions showed no significant difference (P=0.5), Magnesium Sulfate compared to benzene three phenol in treatment of threatened abortion rate RR was 1.09 (95% Ci, 1.16 1.03~), adverse reaction The value of RR was 0.02 (95% CI 0.01~0.05). Conclusion benzene three phenol in treatment of threatened abortion is more effective than Magnesium Sulfate, and the incidence of adverse events was reduced.

【作者單位】： 揚(yáng)州大學(xué)臨床醫(yī)學(xué)院臨床醫(yī)學(xué)系;
【分類號(hào)】：R714.21
【正文快照】： 晚期先兆流產(chǎn)指12至27周出現(xiàn)的陰道出血,下腹脹痛,宮口未開未消,胎兒存活。治療先兆流產(chǎn)的主要原則是利用宮縮抑制劑,抑制宮縮,使胎兒孕齡達(dá)到28周以后,提高胎兒的存活率。目前國內(nèi)的宮縮抑制劑主要有硫酸鎂、間苯三酚、鹽酸利托君、阿托西班等藥物。本文通過收集國內(nèi)現(xiàn)有的資，

本文編號(hào)：1392218