【摘要】：目的:探討1.5T氫質(zhì)子磁共振波譜成像(MRS)在活體正常胰腺中的應用價值及影響因素。方法:采用單體素點分辨波譜(PRESS)序列采集20例健康志愿者的正常胰腺波譜,分析脂質(zhì)峰高(Lip)、峰下面積、脂質(zhì)峰下面積(Lip)/組織內(nèi)水峰下面積(InW)比值與年齡、身高體重指數(shù)(BMI)的相關(guān)性,分析膽固醇和不飽和脂肪酸的混合峰下面積(Chol+UnSat)/脂質(zhì)峰下面積(Lip)比值與年齡、BMI的相關(guān)性。結(jié)果:1.5T活體胰腺MRS掃描成功率為90%(18/20)。Lip峰、TMA峰和Chol+UnSat混合峰顯示率分別為100.0%(18/18)、89%(16/18)和100%(18/18)。Lip峰高與年齡、BMI呈正相關(guān)(r=0.715、0.356),有統(tǒng)計學意義(P=0.01、0.047),峰下面積與年齡、BMI呈正相關(guān)(r=0.503、0.135),與年齡有統(tǒng)計學意義(P=0.033),與BMI無統(tǒng)計學意義(P=0.593)。Lip/InW比值與年齡、BMI呈正相關(guān)(r=0.718、0.563),有統(tǒng)計學意義(P=0.01、0.015)。(Chol+Unsat)/Lip比值與年齡、BMI呈正相關(guān)(r=0.762、0.520),有統(tǒng)計學意義(P=0.000、0.027)。Chol+Unsat峰下面積與年齡、BMI呈正相關(guān)(r=0.519、0.466),有統(tǒng)計學意義(P=0.004、0.000)。結(jié)論:1.5T磁共振波譜成像能夠用于檢測正常活體胰腺的主要代謝物并分析其譜線形態(tài)。
[Abstract]:Objective: to investigate the application value and influencing factors of 1.5T proton magnetic resonance spectroscopy (MRS) in normal pancreas in vivo. Methods: the normal pancreatic spectra of 20 healthy volunteers were collected by monomeric point-resolved spectrum (PRESS) sequence. the correlation between the area under lipid peak height (Lip), peak area, (Lip) / tissue water peak area (InW) ratio and age, body mass index (BMI), cholesterol and saturated fatty acid mixed peak area (Chol UnSat) / lipid subpeak area (Lip) ratio and age were analyzed. The correlation of BMI. Results: the success rate of 1.5T living pancreas MRS scan was 90% (18 鈮，

本文編號：2515189