【摘要】：目的：探討三維能量多普勒血管成像直方圖血流定量分析在甲狀腺結(jié)節(jié)良惡性鑒別診斷中的應(yīng)用價(jià)值。方法：回顧性分析63例患者的69個(gè)甲狀腺結(jié)節(jié),以病理結(jié)果為金標(biāo)準(zhǔn)分為良性病變組及惡性病變組,用三維彩色直方圖血流定量分析比較兩組甲狀腺結(jié)節(jié)定量指標(biāo)：血管指數(shù)(vascularization index,VI)、血流指數(shù)(flow index,FI).血管血流指數(shù)(vascularization flow index,VFI),重復(fù)取樣3次,取平均值,并探討這些指標(biāo)對鑒別甲狀腺結(jié)節(jié)良、惡性的診斷價(jià)值。結(jié)果：所收集的三維多普勒數(shù)據(jù)經(jīng)重建處理后均獲得了較滿意的三維能量多普勒圖像,經(jīng)統(tǒng)計(jì)學(xué)分析后,結(jié)果表明甲狀腺惡性結(jié)節(jié)內(nèi)血流量多于良性結(jié)節(jié),惡性結(jié)節(jié)的血管指數(shù)(vascularization index, VI)、血流指數(shù)(flow index,FI).血管血流指數(shù)(vascularization flow index,VFI)均高于良性結(jié)節(jié),良性病變組與惡性病變組之間的差異均有統(tǒng)計(jì)學(xué)意義(P0.05), ROC曲線分析結(jié)果顯示VI、FI、VFI對甲狀腺結(jié)節(jié)良惡性鑒別診斷均有效,以VI≥0.07為截值診斷甲狀腺結(jié)節(jié)的良惡性,敏感度為97.6%,特異度為71.4%；以FI≥22.67為截值診斷甲狀腺結(jié)節(jié)的良惡性,敏感度為80.5%,特異度為82.1%；以VFI≥1.86為截值診斷甲狀腺結(jié)節(jié)的良惡性,敏感度為87.8%,特異度為78.6%。結(jié)論：三維彩色直方圖血流定量分析在鑒別診斷甲狀腺良惡性腫瘤中有較高的應(yīng)用價(jià)值,可以作為鑒別甲狀腺良惡性腫瘤的定量分析依據(jù)。
[Abstract]:Objective: to evaluate the value of three dimensional power Doppler angiography histogram flow quantitative analysis in the differential diagnosis of benign and malignant thyroid nodules. Methods: 69 thyroid nodules in 63 patients were analyzed retrospectively. according to the pathological results, they were divided into benign lesion group and malignant lesion group. The quantitative indexes of thyroid nodules in the two groups were compared by three-dimensional color histogram blood flow quantitative analysis: vascular index (vascularization index,VI) and blood flow index (flow index,FI). Vascular blood flow index (vascularization flow index,VFI), repeated sampling for 3 times, the average value was taken, and the diagnostic value of these indexes in differential diagnosis of benign and malignant thyroid nodules was discussed. Results: the three-dimensional Doppler data were reconstructed and satisfactory three-dimensional power Doppler images were obtained. after statistical analysis, the results showed that the blood flow in malignant thyroid nodules was higher than that in benign nodules, and the vascular index (vascularization index, VI), blood flow index (flow index,FI) of malignant nodules was higher than that of benign nodules. The vascular blood flow index (vascularization flow index,VFI) was higher than that of benign nodules. The difference between benign lesion group and malignant lesion group was statistically significant (P 0.05), ROC curve analysis showed that VI,FI,VFI was effective in the differential diagnosis of benign and malignant thyroid nodules. The sensitivity and specificity of VI 鈮，

本文編號：2510649