【摘要】：目的:探討1.5TDWI對肺內良、惡性病變的鑒別診斷價值及b值的優(yōu)化。方法:搜集40例經病理/臨床證實的肺內良、惡性病變患者(惡性病變23例,良性病變17例)的影像及臨床資料,40例均經MSCT檢查發(fā)現肺部病變,并行常規(guī)T1WI、T2WI以及多b值DWI(b=0,300,600,1000s/mm2)檢查,測量3組b值測得的ADC值,分析不同b值對圖像質量、信噪比(SNR)、對比噪聲比(CNR)的影響,根據受試者工作特征(ROC)曲線評價不同b值下ADC值鑒別肺部良、惡性病變的診斷效能;并比較同一b值下良、惡性病變ADC值的差異。結果:隨著b值的增加,DWI圖像信號逐漸增高,ADC、SNR及CNR值逐漸下降;b值為300和600s/mm2兩組圖像SNR值差異無統(tǒng)計學意義(P0.05),b值為300與1000s/mm2以及600與1000s/mm2兩組SNR值差異均具有統(tǒng)計學意義(P均0.05);CNR值在兩兩組間的差異均具有統(tǒng)計學意義(P均0.05)。b值為300、600和1000s/mm2時,ROC的曲線下面積(AUC)分別為0.78、0.83和0.81,且均具有診斷意義(AUC均0.5),當b=600s/mm2時,診斷效能最高。在同一b值下,惡性病變圖像信號高于良性病變,且ADC值低于良性病變(P均0.05)。結論:1.5T DWI多b值胸部掃描有助于鑒別肺內良、惡性病變,當b=600s/mm2時,對肺良、惡性病變的鑒別診斷效能最高。
[Abstract]:Objective: To study the value of 1.5TDWI in the differential diagnosis of benign and malignant lesions of the lung and the optimization of the b-value. Methods: The images and clinical data of 40 cases of benign and malignant lesions (23 cases of malignant lesions and 17 benign lesions) in 40 cases of benign and malignant lesions of the lung were collected, and 40 cases were examined by MSCT to find the lung lesions, the normal T1WI, T2WI and the multi-b value DWI (b = 0,300,600,1000 s/ mm2). The effect of different b-value on image quality, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) was measured by measuring the ADC value measured in the 3-group b-value. The difference of the ADC values of benign and malignant lesions in the same b-value was compared. Results: With the increase of b value, the signal of DWI was gradually increased, and the value of ADC, SNR and CNR decreased gradually. The difference of SNR between the two groups with a value of 300 and 600 s/ mm2 was not statistically significant (P0.05), and the b value was 300 and 1000 s/ mm2 and the difference of SNR values between 600 and 1000s/ mm2 had statistical significance (P <0.05). The value of CNR was statistically significant between the two groups (P <0.05). The area under the curve of the ROC (AUC) was 0.78, 0.83, and 0.81, respectively, with a b value of 300,600 and 1000 s/ mm2, and the diagnostic efficacy was the highest when b = 600 s/ mm2. At the same b value, the malignant lesion image signal was higher than the benign lesion and the ADC value was lower than the benign lesion (P 0.05). Conclusion: The chest scan of 1.5T DWI multi-b value can be used to identify the benign and malignant lesions of the lung, and when b = 600 s/ mm2, the differential diagnosis of the benign and malignant lesions of the lung is the highest.
【作者單位】： 中國醫(yī)科大學附屬第四醫(yī)院放射科;
【基金】：遼寧省自然科學基金資助項目(201302/035)
【分類號】：R734.2;R445.2

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相關期刊論文 前8條

1 劉海東;于鐵鏈;劉穎;葉寧;;肺惡性腫瘤和實性良性病變擴散加權成像技術初探[J];國際醫(yī)學放射學雜志;2010年03期

2 李菲;于鐵鏈;李偉棟;張，

本文編號：2501137