【摘要】：目的:探討1.5TDWI對(duì)肺內(nèi)良、惡性病變的鑒別診斷價(jià)值及b值的優(yōu)化。方法:搜集40例經(jīng)病理/臨床證實(shí)的肺內(nèi)良、惡性病變患者(惡性病變23例,良性病變17例)的影像及臨床資料,40例均經(jīng)MSCT檢查發(fā)現(xiàn)肺部病變,并行常規(guī)T1WI、T2WI以及多b值DWI(b=0,300,600,1000s/mm2)檢查,測(cè)量3組b值測(cè)得的ADC值,分析不同b值對(duì)圖像質(zhì)量、信噪比(SNR)、對(duì)比噪聲比(CNR)的影響,根據(jù)受試者工作特征(ROC)曲線評(píng)價(jià)不同b值下ADC值鑒別肺部良、惡性病變的診斷效能;并比較同一b值下良、惡性病變ADC值的差異。結(jié)果:隨著b值的增加,DWI圖像信號(hào)逐漸增高,ADC、SNR及CNR值逐漸下降;b值為300和600s/mm2兩組圖像SNR值差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),b值為300與1000s/mm2以及600與1000s/mm2兩組SNR值差異均具有統(tǒng)計(jì)學(xué)意義(P均0.05);CNR值在兩兩組間的差異均具有統(tǒng)計(jì)學(xué)意義(P均0.05)。b值為300、600和1000s/mm2時(shí),ROC的曲線下面積(AUC)分別為0.78、0.83和0.81,且均具有診斷意義(AUC均0.5),當(dāng)b=600s/mm2時(shí),診斷效能最高。在同一b值下,惡性病變圖像信號(hào)高于良性病變,且ADC值低于良性病變(P均0.05)。結(jié)論:1.5T DWI多b值胸部掃描有助于鑒別肺內(nèi)良、惡性病變,當(dāng)b=600s/mm2時(shí),對(duì)肺良、惡性病變的鑒別診斷效能最高。
[Abstract]:Objective: To study the value of 1.5TDWI in the differential diagnosis of benign and malignant lesions of the lung and the optimization of the b-value. Methods: The images and clinical data of 40 cases of benign and malignant lesions (23 cases of malignant lesions and 17 benign lesions) in 40 cases of benign and malignant lesions of the lung were collected, and 40 cases were examined by MSCT to find the lung lesions, the normal T1WI, T2WI and the multi-b value DWI (b = 0,300,600,1000 s/ mm2). The effect of different b-value on image quality, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) was measured by measuring the ADC value measured in the 3-group b-value. The difference of the ADC values of benign and malignant lesions in the same b-value was compared. Results: With the increase of b value, the signal of DWI was gradually increased, and the value of ADC, SNR and CNR decreased gradually. The difference of SNR between the two groups with a value of 300 and 600 s/ mm2 was not statistically significant (P0.05), and the b value was 300 and 1000 s/ mm2 and the difference of SNR values between 600 and 1000s/ mm2 had statistical significance (P <0.05). The value of CNR was statistically significant between the two groups (P <0.05). The area under the curve of the ROC (AUC) was 0.78, 0.83, and 0.81, respectively, with a b value of 300,600 and 1000 s/ mm2, and the diagnostic efficacy was the highest when b = 600 s/ mm2. At the same b value, the malignant lesion image signal was higher than the benign lesion and the ADC value was lower than the benign lesion (P 0.05). Conclusion: The chest scan of 1.5T DWI multi-b value can be used to identify the benign and malignant lesions of the lung, and when b = 600 s/ mm2, the differential diagnosis of the benign and malignant lesions of the lung is the highest.
【作者單位】： 中國(guó)醫(yī)科大學(xué)附屬第四醫(yī)院放射科;
【基金】：遼寧省自然科學(xué)基金資助項(xiàng)目(201302/035)
【分類號(hào)】：R734.2;R445.2

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相關(guān)期刊論文 前8條

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本文編號(hào)：2501137