【摘要】：目的探討不同形式位移經(jīng)校正后對(duì)MRS結(jié)果可重復(fù)性的影響。方法納入20名被試者于無(wú)位移、平動(dòng)位移、平動(dòng)-轉(zhuǎn)動(dòng)位移時(shí)分別進(jìn)行MRS掃描,每次間隔10min,位移狀態(tài)掃描前由SPM軟件自動(dòng)獲取VOI位置,測(cè)量并比較平動(dòng)位移、平動(dòng)-轉(zhuǎn)動(dòng)位移經(jīng)校正后VOI內(nèi)N-乙酰天門(mén)冬氨酸(NAA)、肌酸(Cr)、磷酸肌酸(PCr)和膽堿復(fù)合物(Cho)含量及NAA/(Cr+PCr)和Cho/(Cr+PCr);計(jì)算上述參數(shù)位移對(duì)比無(wú)位移時(shí)差異性系數(shù)(CV)和重復(fù)性指數(shù)(RI)。結(jié)果平動(dòng)位移經(jīng)校正后各參數(shù)與無(wú)位移間差異均無(wú)統(tǒng)計(jì)學(xué)意義(P均0.05),平動(dòng)-轉(zhuǎn)動(dòng)位移經(jīng)校正后除Cr外,NAA、Cho、NAA/Cr+PCr、Cho/Cr+PCr與無(wú)位移間差異均有統(tǒng)計(jì)學(xué)意義(P均0.01)。平動(dòng)位移和平動(dòng)-轉(zhuǎn)動(dòng)位移經(jīng)校正后與無(wú)位移時(shí)比較,NAA、Cho、Cr含量及NAA/(Cr+PCr)、Cho/(Cr+PCr)的平均CV均12%,重復(fù)性可接受;RI值除Cr外,余參數(shù)均20%,重復(fù)性可接受。結(jié)論 MRS中對(duì)患者頭部平動(dòng)位移可準(zhǔn)確校正,所得結(jié)果重復(fù)性較好。
[Abstract]:Objective to investigate the effect of different displacement forms on repeatability of MRS results after correction. Methods Twenty subjects were scanned with MRS at the time of no displacement, translational displacement and rotational displacement. The VOI position was automatically obtained by SPM software before the displacement state scan, and the translational displacement was measured and compared. The content of N-acetylaspartate (NAA), creatine (Cr), creatine (PCr) and choline complex (Cho) and NAA/ (Cr PCr) and Cho/ (Cr PCr); in VOI after translational and rotational displacement correction The difference coefficient (CV) and repeatability index (RI). When calculating the displacement comparison of the above parameters and no displacement Results there was no significant difference between the parameters of the translational displacement and the non-displacement after correction (P 0.05). After the correction of the translational and rotational displacement, NAA,Cho,NAA/Cr PCr, was obtained except for Cr. There was significant difference between Cho/Cr PCr and no displacement (P0.01). The NAA,Cho,Cr content and the average CV of NAA/ (Cr PCr), Cho/ (Cr PCr) were 12, and repeatability was acceptable, compared with those without displacement after the correction of the translational displacement and the dynamic-rotational displacement. With the exception of Cr, the RI values were 20 and the repeatability was acceptable. Conclusion the head displacement can be corrected accurately in MRS, and the results are reproducible.
【作者單位】： 同濟(jì)大學(xué)附屬同濟(jì)醫(yī)院醫(yī)學(xué)影像科;上海市磁共振重點(diǎn)實(shí)驗(yàn)室;
【分類(lèi)號(hào)】：R445.2

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