【摘要】：目的比較超聲引導(dǎo)下聚桂醇和平陽霉素介入治療靜脈畸形的效果。方法回顧性分析我院介入治療的53例靜脈畸形患者的臨床資料,按治療方法不同分為平陽霉素組27例與聚桂醇組26例。在實時超聲引導(dǎo)下,單用平陽霉素或聚桂醇注射治療。4周注射1次,4次為1個療程。治療前超聲評估畸形靜脈腔的體積;療程結(jié)束后6個月觀察臨床療效及超聲評估畸形靜脈腔的體積縮小情況。觀察術(shù)后近遠期并發(fā)癥,如肺栓塞、皮膚潰瘍、局部腫脹、發(fā)熱等。結(jié)果 53例患者均完成1個療程治療,并于療程結(jié)束后6個月隨訪1次。治療前,2組畸形靜脈腔的體積差異無統(tǒng)計學(xué)意義(P0.05);治療后,聚桂醇組畸形靜脈腔的體積小于平陽霉素組,差異有統(tǒng)計學(xué)意義(P0.01);2組治療后畸形靜脈腔的體積均較治療前明顯縮小,差異有統(tǒng)計學(xué)意義(P0.01)。隨訪6個月時,平陽霉素組治愈率37.0%(10/27),聚桂醇組治愈率88.5%(23/26),差異有統(tǒng)計學(xué)意義(Z=3.838,P0.01)。聚桂醇組治療均未出現(xiàn)肺栓塞。聚桂醇組并發(fā)癥發(fā)生率為30.8%(8/26),差異無統(tǒng)計學(xué)意義(P0.05),平陽霉素組為18.5%(5/27),差異無統(tǒng)計學(xué)意義(2χ=0.536,P0.05)。結(jié)論對于畸形腔隙大、位置深在、回流速度快的靜脈畸形,超聲引導(dǎo)下聚桂醇泡沫硬化治療效果優(yōu)于平陽霉素,且兩者并發(fā)癥發(fā)生率無差異。
[Abstract]:Objective to compare the effect of interventional treatment of venous malformation with polycinolol and pingyangmycin under ultrasound guidance. Methods the clinical data of 53 patients with venous malformation treated by interventional therapy in our hospital were retrospectively analyzed. According to different treatment methods, 27 cases were divided into Pingyangmycin group (n = 27) and polycinnamol group (n = 26). Under the guidance of real-time ultrasound, pingyangmycin or polycinnamol were injected only once in 4 weeks and 4 times as a course of treatment. The volume of anomalous venous cavity was evaluated by ultrasound before treatment, the clinical effect was observed 6 months after treatment and the volume reduction of deformed venous cavity was evaluated by ultrasound. To observe the postoperative complications, such as pulmonary embolism, skin ulcer, local swelling, fever and so on. Results all 53 patients completed a course of treatment and were followed up 6 months after the end of the course. Before treatment, there was no significant difference in volume of malformed venous cavity between the two groups (P0.05); after treatment, the volume of venous cavity in polycinnamol group was smaller than that in pingyangmycin group (P0.01). After treatment, the volume of venous cavity in both groups was significantly smaller than that before treatment (P0.01). The cure rate was 37.0% (10 / 27) in Pingyangmycin group and 88.5% (23 / 26) in polycinnamol group (P 0.01). No pulmonary embolism was found in the polycinnamol group. The incidence of complications in polycinnamol group was 30.8% (8 / 26), the difference was not statistically significant (P0.05), and that in Pingyangmycin group was 18.5% (5 / 27), and there was no significant difference (蠂 ~ 2 = 0.536). Conclusion for venous malformation with large lacunae, deep position and fast reflux rate, the effect of polycinnamol foam sclerosis under ultrasound guidance is better than that of pingyangmycin, and there is no difference in the incidence of complications between the two groups.
【作者單位】： 蚌埠醫(yī)學(xué)院第一附屬醫(yī)院功能科;
【分類號】：R445.1;R543.6

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