【摘要】：目的:探討磁共振DWI聯(lián)合DCE-MRI診斷早期強(qiáng)直性脊柱炎的臨床應(yīng)用價(jià)值。方法:回顧性搜集48例臨床早期活動(dòng)性強(qiáng)直性脊柱炎患者影像資料,分析其DWI及DCE序列圖像,分別測(cè)量骶側(cè)髂側(cè)關(guān)節(jié)面下骨髓的ADC值,并與21例健康志愿者的資料進(jìn)行對(duì)比分析,計(jì)算增強(qiáng)因子Fenh、增強(qiáng)斜率Senh和達(dá)峰時(shí)間Tmax,并與正常組對(duì)照,繪制病例組時(shí)間-信號(hào)曲線(TIC),對(duì)ADC值與Fenh、Senh值之間關(guān)系進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:病例組髂骨側(cè)關(guān)節(jié)面下骨髓區(qū)ADC平均值為(5.05±1.10)×10-4 mm2/s,骶骨側(cè)為(4.63±0.79)×10-4 mm2/s,均較對(duì)照組增高;病例組骨髓區(qū)Fenh、Senh高于對(duì)照組,Tmax低于正常值;病例組TIC表現(xiàn)為Ⅱ型,Ⅲ型;病變區(qū)ADC值與Fenh值之間呈高度直線相關(guān)關(guān)系(P0.05),相關(guān)系數(shù)r=0.705。結(jié)論:磁共振DWI及DCE-MRI對(duì)早期AS患者骶髂關(guān)節(jié)骨髓異常改變顯示敏感;病變區(qū)ADC值與Fenh值相結(jié)合,增強(qiáng)了早期診斷本病的信心,提供了影像診斷的新思路。
[Abstract]:Objective: to evaluate the clinical value of magnetic resonance (DWI) combined with DCE-MRI in the diagnosis of early ankylosing spondylitis (ankylosing spondylitis). Methods: the imaging data of 48 patients with active ankylosing spondylitis were collected retrospectively and their DWI and DCE sequences were analyzed. The ADC values of the sacral iliac subarticular bone marrow were measured respectively. The data of 21 healthy volunteers were compared and analyzed. The enhancement factor Fenh, enhancement slope Senh and peak time Tmax, were calculated and compared with the control group. The ADC value and Fenh, value of (TIC), were drawn. The relationship between Senh values was analyzed statistically. Results: the average value of ADC in the bone marrow area of the iliac side was (5.05 鹵1.10) 脳 10 ~ (-4) mm2/s, in the case group and (4.63 鹵0.79) 脳 10 ~ (-4) mm2/s, in the sacral side of the iliac bone side, which was higher than that in the control group. The Fenh,Senh of bone marrow area in the case group was higher than that of the control group, the Tmax was lower than the normal value; the TIC of the case group was type 鈪，

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